n-octacosanol is an normolipidemic aliphatic primary alcohol obtained from the plant Tinospora cordifolia Miers. In the present study, the plant stems were collected from five accessions namely Anniyalam, Chennai, Hassan, Vishakhapatnam and Bangalore between June and August. Later a simple HPTLC method has been established for determination of n-octacosanol in methanolic extracts of all these g...

The present study deals with the antimicrobial activity and phytochemical screening of the two medicinal plants, Tinospora cordifolia and Euphorbia hirta those are commonly available in India. Results of antimicrobial activity revealed that these medicinal plant extracts were very effective against Serratia marcescens, E. coli, Streptococcus thermophilus, Fusarium oxysporium, Aspergillus niger ...

The effectiveness of aqueous extract of seven locally available medicinal plants i.e. Trachyspermum ammi (seeds), Zingiber officinale (rhizome), Tinospora cordifolia (leaves), Cymbopogon citratus (leaves), Moringa oleifera (bark) were evaluated against the plant pathogenic fungus i.e. Fusarium oxysporum f. sp. lini (causing wilt in linseed). The plant extracts were screened for their antagonist...

OBJECTIVES To assess the safety and efficacy of TCE in human immuno-deficiency virus positive patients. MATERIALS AND METHODS Efficacy of Tinospora cordifolia extract (TCE) in HIV positive patients was assessed in randomized double blind placebo controlled trial. 68 HIV positive participants were randomly assigned to two groups to receive either TCE or placebo for six months. After clinical e...

The aim of the present study was to evaluate the antimicrobial activity of Tinospora cordifolia extracts against three standard ATCC strains of Escherichia coli, Staphylococcus aureus and Pseudomonas aeruginosa. The efficacy of extract was measured in terms of Minimum Inhibitory Concentration (MIC), Minimum Bactericidal Concentration (MBC) and zone of inhibition (mm). Antimicrobial activity of ...

Antimicrobial and Antioxidant Potential of Tinospora Cordifolia were performed by In-vitro Methods. For this study stem plant cordifolia where collected dried under shade. Morphological characteristics Physio-chemical parameters investigated. Plant materials extracted Soxhlet extraction method then Pharmacognostical evaluation extract was subjected to various phytochemical tests for preliminary...

In this study, the RAPD (Random Amplified Polymorphic DNA) technique was employed for determination of the components in an Ayurvedic herbal prescription, Rasayana Churna. One-hundred-and-twenty decamer oligonucleotide primers were screened in the RAPD analysis to identify three Ayurvedic medicines, dried stem of Tinospora cordifolia, dried fruit of Emblica officinalis and dried fruit of Tribul...

Depression is a complex psychiatric disorder characterized by depressed mood, anhedonia, loss of energy and low self esteem. Nitric oxide (NO) is the smallest biologically active molecules which plays an important role in the intracellular signaling. NO negatively controls the levels of 5-HT. Inhibition of NO synthases (NOS) which are responsible for the production of NO; may exert antidepressa...

The study evaluated the in vitro iron chelating, lipid peroxidation inhibitory and DNA protective activities of hydroalcoholic (60% ethanolic) extracts of various plant parts of Terminalia chebula, Caesalpinia crista, Cajanus cajan, Terminalia belerica, Emblica officinalis, and Tinospora cordifolia. The iron chelating property of the plants is in accordance with the order of their IC50 values f...

background: radiotherapy is the main modality of cancer treatment. there are many chemical radioprotectors which unfortunately have lethal or toxic effect. therefore the search is on to find out natural plant based radioprotectors. a well known medicinal plant,which is more acceptable to the body, tinospora cordifolia, was tested in animal tissues against gamma radiations. radioprotective effec...