Background: New Pressor Protein (NPP) is a human plasma enzyme structurally related to b–fragment of activated factor XІІ (β-FXIIa). The objective of the present study was to investigate the effects of NPP and β-FXIIa on systolic blood pressure and heart rate in bilateral nephrectomized rats. Methods: Forty male Wistar rats (250-300 g) were sham-operated or bilaterally nephrectomized under anes...

This study validated the RisingSun RS-651 blood pressure (BP) monitor based on auscultation in adults according to the American National Standards Institute/Association for the Advancement of Medical Instrumentation/International Organization for Standardization (ANSI/AAMI/ISO) 81060-2:2013 standard. The RS-651 device was evaluated in a study of 97 participants. The same arm simultaneous method...

Over the years, we have learned through a large number of studies, initially observational ones, and then intervention ones, that, if on the one side cardiovascular risk increases with BP levels from 115/75 mm Hg on, doubling with every 20-mmHg increase in systolic BP (SBP) and 10-mmHg increase in diastolic BP (DBP), on the other, cardiovascular risk decreases significantly with BP reduction by...

But what do we do when one number is at goal and the other is not? It is clear that in individuals younger than 50 years, diastolic BP (DBP) is the better predictor of future complications of hypertension, whereas in those 50 years and older, systolic BP (SBP) is a better predictor of future complication risk. Most individuals with hypertension are 50 years or older, and for these patients, SBP...

BACKGROUND Orthostatic hypotension (OH), a blood pressure drop after postural change, is associated with impaired standing balance and falls in older adults. This study aimed to assess the association between blood pressure (BP) and a measure of quality of standing balance, i.e. Center of Pressure (CoP) movement, after postural change from supine to standing position in geriatric outpatients, a...

High blood pressure (BP), a major established predictor of cardiovascular disease, is the leading risk factor for mortality worldwide.1,2 Both systolic BP (SBP) and diastolic BP (DBP) have continuous, independent relations with the risk of cardiovascular disease3; however, considerable uncertainty persists about the relative importance of SBP, DBP, and their combination in predicting cardiovasc...

OBJECTIVE This study examined the effect of parity on blood pressure (BP) readings and BMI among rural West African Dogon women. DESIGN Correlational research design. SETTING Sangha, West Africa PARTICIPANTS 133 West African Dogon Women METHODS Demographic survey including age, number of children, history of hypertension, and village affiliation. BP readings were taken in accordance wit...