Superoxide dismutases might conceivably protect against both ionizing radiation and free radical-producing antibiotic antitumor drugs. Copperand zinc-containing Superoxide dismutase (CuZn Superoxide dismutase) and manganese-contain ing Superoxide dismutase (Mn Superoxide dismutase) were specifically assayed in human malignant tumors and for com parison in human tissues. The tumors possessed les...

three levels of lysine (90, 100 and 110% of ross requirement) and of pyridoxine (3, 6 and 9 mg kg-1) were used in a 3 × 3 factorial experiment to investigate the growth and blood antioxidant ability of broilers under high ambient temperature. none of the dietary supplements affected the weight gain during the starter and grower periods. although no significant differences were detected between ...

The vascular endothelium is important for the early and late effects observed in lethally irradiated tissue and organs. We examined the effects of exogenously added superoxide dismutase on cell survival and angiogenesis in lethally irradiated human primary umbilical vein endothelial cells. Cell survival was significantly improved in superoxide dismutase-treated cells; the addition of superoxide...

A common cause of amyotrophic lateral sclerosis (ALS) is mutations in the gene encoding superoxide dismutase-1. There is evolving circumstantial evidence that the wild-type protein can also be neurotoxic and that it may more generally be involved in the pathogenesis of ALS. To test this proposition more directly, we generated mice that express wild-type human superoxide dismutase-1 at a rate cl...

The activity of superoxide dismutase isoenzymes was determined in knee joint synovial fluid from 21 patients with rheumatoid arthritis, nine patients with reactive arthritides, and from 17 patients before arthroscopy or arthrotomy for suspected meniscal or ligament injury (controls). Extracellular superoxide dismutase was the major isoenzyme and accounted for about 80% of the total superoxide d...

The microstructures and mechanical properties of (Cu0.5Zr0.5)100−xZnx (x = 0, 1.5, 2.5, 4.5, 7, 10, and 14 at. %) bulk metallic glass (BMG) composites were studied. CuZr martensitic crystals together with minor B2 CuZr and amorphous phases dominate the OPEN ACCESS

and Applied Analysis 3 2. Main Results and Proofs Lemma 2.1. For α α1, . . . , αn ∈ D, let uα z1, . . . , zn ∏n j 1 1 − |αj |2 / 1 − αjzj . Then uα z1, . . . , zn ∈ Lφa D , and ‖uα z ‖σn ≤ 1 φ−1 ∏n j 1 ( 1/δ2 j )) . 2.1 Proof. It is easy to see that ‖uα z ‖∞ ∏n j 1 1 |αj | / 1 − |αj | 2 ∏n j 1 2 − δj /δj . Since φ 0 0, the convexity of φ implies φ ax ≤ aφ x for 0 ≤ a ≤ 1. Hence, for every C > 0...

Extracellular-superoxide dismutase is a tetrameric copper-containing glycoprotein that previously has been demonstrated to be the major superoxide dismutase of human extracellular fluids. The occurrence of this enzyme in various human tissues that were removed from two accidental death victims and in 19 different human cultured cell lines was determined. All investigated tissues were found to c...

Enzymatic superoxide-dismutase activity is believed to be important in defense against the toxic effects of superoxide. Although superoxide dismutases are among the best studied proteins, numerous questions remain concerning the specific biological roles of the various superoxide-dismutase types. In part, this is because the proposed damaging effects of superoxide are manifold, ranging from ina...