The immunoglobulin (Ig) protein domain is widespread in nature having a well-recognized role in proteins of the immune system. In this review, we describe the proteins containing Ig-like domains in Escherichia coli and enterobacteria, reporting their structural and functional properties, protein folding, and diverse biological roles. In addition, we cover the expression of heterologous Ig domai...

Hepatitis E virus (HEV) is a major cause of hepatitis. We evaluated five HEV antibody diagnostic assays by using outbreak specimens. The Abbott immunoglobulin G (IgG), Genelabs IgG, and Walter Reed Army Institute of Research (WRAIR) IgM assays were about 90% sensitive; the Abbott IgG and WRAIR total Ig and IgM assays were more than 90% specific.

S i i r face d ig i t i za t ion is a m e t h o d for ob ta in ing threed i m e ii s i o ii. a1 11% eas tire in e nt of a i i 11 iikii o zuii surf (1 ce . Tlie p e r f o r m a n c e a n d qua l i t y of d ig i t i za t ion are depeiirleirt iipoii t h e choice o f d ig i t i z ing dev ices aiid approaches . An efJicieizt d ig i t i z ing m e t h o d i i o t oiily reduces t h e elapsed t i m e of...

P H O T O S : (L E F T T O R IG H T ) M V A L IG U R S K Y / IS T O C K P H O T O ; N N P H O T O S / S H U T T E R S T O C K effects of DNA damage and defects in DNA repair processes. Knowledge of how specific signatures originate could have a major impact on cancer diagnosis and prevention. One approach to address this question is to reproduce the signatures in experimental systems by genetic...

Scavenger receptor (SR)-specific delivery by maleylation of a ubiquitous self-protein, Ig, to SR-bearing APCs results in self-limiting induction of autoimmune effects in vivo. Immunization with maleyl-Ig breaks T cell tolerance to self-Ig and causes hypergammaglobulinemia, with increases in spleen weight and cellularity. The majority of splenic B cells show an activated phenotype upon maleyl-Ig...

Introduction A case report of an 50 years old patient which started 14 years ago , with an severe onset – glotic edema with anaphylaxis, after a second intake of Rocephin (Sodium Ceftriaxone) and also due to an emotional distress and associated with a malfunction of the thyroid status. He develops within a 3 year period of time a multiple drug hypersensitivity syndrome to beta lactam and non be...

Allotype suppressor T-cell (Ts) populations that persist for the life of the animal arise in (BALB/c x SJL)F(1) hybrids exposed perinatally to antibody to the paternal (Ig-1b) allotype on IgG(2a)-isotype immunoglobulin H chains. These Ts suppress Ig-lb production by depleting the supply of allotype- specific helper T cells (Th) required, in addition to carrier-specific Th, for the latter stages...

T cell-dependent Ig production involves interaction between T cells and B cells. This study evaluated the effects of prostaglandin (PG) E(2) on Ig production in a system in which B cells were co-cultured with autologous CD4(+) T cell clones non-specifically activated by anti-CD3. The effects of PGE(2) on T cell-dependent Ig production differed substantially, depending on the T cells employed. W...

Examining the interplay of genes, experience and the brain is crucial to understanding psychopathology. We review the recent gene-environment interaction (G×E) and imaging genetics literature with the goal of developing models to bridge these approaches within single imaging gene-environment interaction (IG×E) studies. We explore challenges inherent in both G×E and imaging genetics and highligh...

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