نتایج جستجو برای: spatial learning

تعداد نتایج: 940892  

Journal: :iranian journal of pharmaceutical research 0
a talebi n naghdi h sepehri a rezayof

the hippocampal system plays an important role in memory function. neurohormones like androgens and estrogens that syntheses in hippocampus have an important role in learning and memory. many biological effects of estrogens in the brain via estrogenic receptors (ers) are investigated. the current research has conducted to assess the effect of estrogenic receptors on spatial discrimination in ra...

Journal: :iranian journal of basic medical sciences 0
ali moghimi department of biology, faculty of sciences, ferdowsi university of mashhad, iran javad baharara department of biology, faculty of basic sciences, islamic azad university, mashhad branch, iran saideh samareh musavi department of biology, faculty of basic sciences, islamic azad university, mashhad branch, iran

objective(s) the possible risks of radio-frequency electromagnetic fields (emf) for the living organisms and human body are a growing concern for our society. in this study, we examined the possibility of changes in working memory and hippocampal histological characteristics effects in mice brain following whole body exposure to microwave radiation. materials and methods during gestation period...

Introduction: Cognitive impairment is commonly associated with pain. The modulatory role of orexin 1 receptor (OX1R) in pain pathways as well as learning and memory processes is reported in several studies. The current study was designed to investigate the possible role of CA1-hippocampal OX1R on spatial learning and memory of rats following capsaicin-induced orofacial pain. Methods: Orofacial...

Amin Taleb Ghobadi Amir Farshchi, Golbarg Ghiasi Samireh Farshchi

Objective(s) Diabetes mellitus is associated with disturbances of learning and memory and cognitive functioning. Aegle marmelos Corr. from Rutaceae family is widely used in Iranian folk medicine for the treatment of diabetes mellitus. Considering the beneficial antidiabetic and antioxidant potential of A. marmelos, this study was conducted to evaluate the effect of oral administration of A. ma...

Ali Pourmotabbed, Entezar Mehrabinasab, Seyed Ershad Nedaei,

Introduction: It has been reported that oral morphine dependency facilitated formation of spatial learning and memory. In the present study the role of NMDA receptors located in hippocampal CA1 area of morphine dependent rats was studied. Methods: Male rats were divided into 4 groups. Two cannulae were stereotaxically implanted bilaterally into the hippocampal CA1 area. After 5 days recover...

Ali Pourmotabbed, Haydeh Haghighizad, Hedayat Sahraei, Mohammad Kamalinejad, Mohammad Rasoul Ghadami, Sara Ghadami,

Introduction: It has been reported that acute administration of morphine impairs learning and memory processes in rats. Furthermore, recent studies showed that Saffron extract improved ethanol-induced impairments of learning behaviors in mice, and also prevented ethanol-induced inhibition of hippocampal long-term potentiation. It can be postulated that there are some common mechanisms respon...

Journal: :the iranian journal of pharmaceutical research 0
soheila babanejad department of physiology and pharmacology, pasteur institute, tehran, iran. department of physiology, faculty of sciences, tehran university, tehran, iran. nasser naghdi department of physiology and pharmacology, pasteur institute, tehran, iran. seyyed ali haeri rohani department of physiology, faculty of sciences, tehran university, tehran, iran.

ca1 region of hippocampus has an important role in learning and memory. previous reports have shown that androgens like testosterone and its metabolites are present in high concentration in ca1 region of hippocampus. androgen receptors have also high density in this region. therefore, it is suggested that neurohormones in ca1 have an important role in learning and memory. it is likely that test...

Ali Pourmotabbed, Atefeh Touhidi, Parviz Imani, Parychehr Yaghmaei, Seyed Ershad Nedaei,

Introduction: There are evidences showing the role of nitric oxide in the opiate reward properties. The role of nitric oxide signaling pathway as an intracellular mechanism on augmentation of long term potentiation in hippocampal CA1 area of rats is also confirmed. It has been also reported that oral morphine dependence facilitates formation of spatial learning and memory via activation of N...

آفرینش خاکی, محمدرضا, زمانی, نسترن, معاضدی, احمدعلی, پور مهدی بروجنی, مهدی,

Background and Objective: Docosahexaenoic acid (DHA) is the major polyunsaturated fatty acid in the brain and a structural component of neuronal membranes. The present study aimed to examine the effect of DHA on spatial learning and memory in an electrical obliteration of nucleus basalis magnocellularis (NBM) model of Alzheimer's disease. Materials and Methods: In this study 56 adult male Wist...

Journal: Addiction and Health 2016
Fatemeh Delavari Khadijeh Esmaeilpour Nouzar Nakhaee, Saeid Esmaeili-Mahani Vahid Sheibani

Background: Disturbances in maternal care have been associated with increased risk for drug abuse later in life. However, there has been little investigation of the effects of maternal separation (MS), a model of early life stress, on nicotine dependence, specifically during adolescence. In the present study, we aimed to investigate the effect of MS on nicotine-conditioned place preference (CPP...

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