نتایج جستجو برای: small supernumerary marker chromosome ssmc

تعداد نتایج: 1015567  

2015
Guillaume Jedraszak Aline Receveur Joris Andrieux Michèle Mathieu-Dramard Henri Copin Gilles Morin

Cat-eye syndrome is a rare genetic syndrome of chromosomal origin. Individuals with cat-eye syndrome are characterized by the presence of preauricular pits and/or tags, anal atresia, and iris coloboma. Many reported cases also presented with variable congenital anomalies and intellectual disability. Most patients diagnosed with CES carry a small supernumerary bisatellited marker chromosome, res...

2012
AB Hamid A Weise M Voigt M Bucksch N Kosyakova T Liehr E Klein

Centromere-near gain of copy number can be induced by intra- or inter-chromosomal rearrangements or by the presence of a small supernumerary marker chromosome (sSMC). Interestingly, partial trisomy to hexasomy of euchromatic material may be present in clinically healthy or affected individuals, depending on origin and size of chromosomal material involved. Here we report the known minimal sizes...

2015
Frenny Sheth Mizanur Rahman Thomas Liehr Manisha Desai Bhumika Patel Chirag Modi Sunil Trivedi Jayesh Sheth

BACKGROUND Children born with congenital anomalies present a very high rate of perinatal death and neonatal mortality. Cytogenetic analysis is a convincing investigation along with clinical suspicion and biochemical screening tests. The current study was designed to characterize the prevalence and types of chromosomal abnormalities in high risk prenatal samples using different cytogenetic techn...

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