Background: Progesterone is indispensable for differentiation of human endometrial stromal cells (HESCs) into decidual cells, a process that critically controls embryo implantation. However, HESCs also abundantly express androgen receptors (AR), yet the role of this member of the superfamily of ligand-dependent transcription factors in the decidual process remains poorly elucidated. Materials a...

Since the first endocannabinoid anandamide was identified in 1992, extensive research has been conducted to characterize the elements of the tightly controlled endocannabinoid signaling system. While it was established that the activity of endocannabinoids are terminated by a two-step process that includes cellular uptake and degradation, there is still a continuing debate about the mechanistic...

Networks exist to provide services to users. Increasingly, the networks on which the services reside are not the same as the networks from which the services are accessed. This leads to the problem on how to best provide such services transparently when the access protocols differ. We discusses a methodology to make available the existing services residing in a network whose protocols are disti...

A message based comparative study between signaling system #7(SS7) and MFC Signaling is done. Here the limitations of SS7 and MFC signaling are also studied. The reasons for the transition from Multi-frequency Coded (MFC) Signaling to SS7 has been discussed.

A unipolar signaling system transmits using intensity or amplitude in multiple dimensions. Typical examples arise in optical transmission or radio communication using MT-MFSK as both the signaling and the modulation technique. There are v dimensions which represent pulses or tones. Each codeword consists of a selection of k of these tones with unit intensity. Each user is assigned m of these bi...

parkinson's disease (pd) is a chronic neurodegenerative condition which has the second largest incidence rate among all other neurodegenerative disorders barring alzheimer's disease (ad). currently there is no cure and researchers continue to probe the therapeutic prospect in cell cultures and animal models of pd. out of several factors contributing to pd prognosis, the role of p38 mapks (mitog...

Dorsoventral pattering relies on Toll and BMP signalling in all insects studied so far, with variations the relative contributions of both pathways. Drosophila beetle Tribolium share extensive dependence Toll, while representatives more distantly related lineages like wasp Nasonia bug Oncopeltus rely strongly signalling. Here, we show that cricket Gryllus bimaculatus , an evolutionarily distant...

Background: Hepatitis C is a global health problem. The exact mechanisms by which hepatitis C virus (HCV) can evade the host immune system have become controversial. Whether HCV polyproteins modulate IFN signalling pathways or HCV proteins are responsible for such a property is the subject of interest. Therefore, an efficient baculovirus delivery system was developed to introduce the whole geno...

Background: A prerequisite for successful embryo implantation is adequate preparation of receptive endometrium and the establishment and maintenance of a viable embryo. The success of implantation further relies upon a two-way dialogue between the embryo and uterus. However, molecular bases of these preimplantation and implantation processes in humans are not well known. Materials and Methods: ...