This paper deals with a question regarding tight closure in characteristic zero which we now review. Let R be a commutative ring of prime characteristic p and let I ⊆ R be an ideal. Recall that for e ≥ 0, the e-th Frobenius power of I, denoted I [p e], is the ideal of R generated by all p-th powers of elements in I. We say that f ∈ I∗, the tight closure of I, if there exists a c not in any mini...

PURPOSE To quantify protein changes in the morphologically distinct remodeling zone (RZ) and adjacent regions of the human lens outer cortex using spatially directed quantitative proteomics. METHODS Lightly fixed human lens sections were deparaffinized and membranes labeled with fluorescent wheat germ agglutinin (WGA-TRITC). Morphology directed laser capture microdissection (LCM) was used to ...

Minimized trans-acting HDV ribozyme systems consisting of three (Rz-3) and two (Rz-2) RNA strands were prepared and their folding conformations were analyzed by NMR spectroscopy. The guanosine residues in one of the enzyme components of Rz-3 were labeled with 13C and 15N. Imino proton signals were assigned by analysis of NOESY and HSQC spectra. The results are consistent with the nested double ...

As the prevalence of active tuberculosis decreases in the United States, the focus on treatment of latent tuberculous infection (LTBI) has intensified. However, the standard 6–9-month course of isoniazid has been burdened with suboptimal rates of therapy completion and concerns about hepatotoxicity and infection with isonia-zid-resistant organisms. These issues have spurred interest in alternat...

Figure S1: RZ Scores using the TFFMs for HB. The x-axis corresponds to the TFFM hit probability / score threshold used for each run. The y-axis corresponds to the RZ score obtained from each run. The RZ scores are highly dependent on the hit probability/score threshold used. More importantly, the highest scores obtained from the TFFMs are lower than those obtained from the best performing gappe...

In this paper, the performance of 10 Gbps optical communication system with the dispersion managed RZ pulse has been reported. The return-to-zero (RZ) pulse is efficient for long-distance, high-bit-rate, wavelength division multiplexed (WDM) transmission dispersion-managed systems. In RZ pulse, the power is transmitted only for fraction of bit period. The effect of varying the dispersion parame...

Two months of treatment with rifampin-pyrazinamide (RZ) and 9 months of treatment with isoniazid are both recommended for treatment of latent tuberculosis infection in adults without human immunodeficiency virus infection, but the relative cost-effectiveness of these 2 treatments is unknown. We used a Markov model to conduct a cost-effectiveness analysis to assess the impact on life expectancy ...

We propose a scheme to achieve regenerative format conversion from a distorted non-return-to-zero-on-off-keying (NRZ-OOK) signal to a return-to-zero-binary-phase-shift-keying (RZ-BPSK) signal of high quality in an integrated device. This proposal is achieved by employing an interferometer on a silicon chip with a coupled ring resonator optical waveguide embedded in one arm. In this scheme the a...

Rnf43 (RING finger protein 43) and Znrf3 (zinc/RING finger protein 3) (RZ) are two closely related transmembrane E3 ligases, encoded by Wnt target genes, that remove surface Wnt (wingless-int) receptors. The two genes are mutated in various human cancers. Such tumors are predicted to be hypersensitive to, yet still depend on, secreted Wnts. We previously showed that mutation of RZ in the intest...

A.1 Studies on Dynamic Migrations We study the impact of dynamic migrations, comparing RAMZzz and RZ–SP (RZ–SP uses the adaptive demotion scheme with no page migration). Figure 1 presents ED results for RAMZzz and RZ–SP on DDR3. RAMZzz has much lower ED than RZ–SP, with an average reduction of 23.3%. The reduction depends on the memory footprint and memory access intensiveness. The reduction is...