Remitting Seronegative Symmetrical Synovitis with Pitting Edema (RS3PE) is an uncommon elderly-onset rheumatic picture descripted for the first time by McCarthy et al. in 1985 [1] characterized by tenosynovitis of extensor tendons at the wrist and (less frequently) at the feet. The edematous imbibition of tendon sheaths determines the “boxing-glove" swelling which can be considered when bilater...

Remitting seronegative symmetrical synovitis with pitting edema (RS3PE) is a rare entity mainly found in elderly males. It is characterized by pitting edema mainly of dorsum of both hands giving a "boxing glove hand" appearance; rarely involving feet also, acute in onset, negative rheumatoid factor and a good response to low dose corticosteroid therapy. Clinically it almost resembles a case of ...

R emitting seronegative symmetrical sy-novitis with pitting edema (RS3PE), first described by McCarty (1), is characterized by symmetrical pitting edema of the hands and feet; tenderness, swelling, and/or limited motion of the joints; fatigue; and fever (1,2). It commonly occurs in elderly people (1,2). We have recently encountered two cases of RS3PE that developed shortly after the initiation ...

We describe the clinical case of a 74-year-old male patient who received second Comirnaty/Pfizer anti-COVID-19 vaccine dose. After 3 weeks he showed signs polymyalgia rheumatica. The history included mild chronic normocytic normochromic anemia and hypogammaglobulinemia, osteoarthritis disease, livedo reticularis, hypercholesterolemia, arterial hypertension. Despite prolonged treatment with NSAI...