نتایج جستجو برای: radioimmunotherapy

تعداد نتایج: 1230  

Journal: :Biomedical Imaging and Intervention Journal 2006

Journal: :Seminars in Nuclear Medicine 2009

Journal: :Clinical cancer research : an official journal of the American Association for Cancer Research 2007
Diane E Milenic Kayhan Garmestani Erik D Brady Paul S Albert Alia Abdulla Joseph Flynn Martin W Brechbiel

PURPOSE Recent studies from this laboratory with (212)Pb-trastuzumab have shown the feasibility of targeted therapy for the treatment of disseminated peritoneal disease using (212)Pb as an in vivo generator of (212)Bi. The objective of the studies presented here was improvement of the efficacy of alpha-particle radioimmunotherapy using a chemotherapeutic agent. EXPERIMENTAL DESIGN In a series...

Journal: :American family physician 2008
David E Gerber Timothy A Chan

Recent advances have improved the effectiveness, decreased the complications, and expanded the implications of radiation therapy. These advances include three-dimensional conformal radiation therapy, intensity-modulated radiation therapy, stereotactic radiotherapy, brachytherapy, and radioimmunotherapy. Each of these modalities has improved radiation targeting, thereby limiting radiation exposu...

2006
Barry W. Wessels

Progress in animal radioimmunotherapy has been reviewed by high lighting 22 successful experiments using human \enografts in rodent models. Significant tumor growth delay has been observed in all experi ments with five groups reporting tumor control 100 days post-tumor implantation. The radiobiological significance of these experiments is analyzed through a proposed framework for the comparison...

Journal: :Cancer research 2007
John M Pagel Anastasia Pantelias Nathan Hedin Shani Wilbur Laura Saganic Yukang Lin Donald Axworthy Donald K Hamlin D Scott Wilbur Ajay K Gopal Oliver W Press

Despite the promise of radioimmunotherapy using anti-CD20 antibodies (Ab) for the treatment of relapsed patients with indolent non-Hodgkin lymphoma (NHL), most patients treated with conventional doses of (131)I-tositumomab or (90)Y-ibritumomab eventually relapse. We did comparative assessments using conventional radioimmunotherapy targeting CD20, CD22, and HLA-DR on human Ramos, Raji, and FL-18...

Journal: :Nature Reviews Cancer 2015

Journal: :Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2009
Robert M Sharkey Habibe Karacay Christine R Johnson Samuel Litwin Edmund A Rossi William J McBride Chien-Hsing Chang David M Goldenberg

UNLABELLED We determined whether therapeutic responses using a bispecific antibody that pretargeted (90)Y-hapten-peptide radioimmunotherapy or a directly radiolabeled, humanized, (90)Y-anti-CD20 IgG (veltuzumab) could be improved by combining these treatments with unlabeled humanized antibodies against CD22 (epratuzumab), CD74 (milatuzumab), or veltuzumab. METHODS Nude mice bearing establishe...

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