Prodrome of paranoid schizophrenia with the episodic type of course (F20.1 and F20.2 according to ICD-10) and the schizoaffective structure of the episode was retrospectively studied. The pronounced and persistent affect, in particular depression in conjunction with hallucinations and/or delusions throughout the whole episode, served as the basis for an episode qualification as the schizoaffect...

Schizophrenia occurs in 1% of the population and is severely impairing to those afflicted. Thereby, it utmost importance recognize treat disorder as early possible. For last several decades research has attempted elucidate a variety predictive factors order aid identification patients at high risk developing schizophrenia spectrum disorder. These have included premorbid or prodromal movement sy...

IMPORTANCE Voltage-gated potassium channel complex antibody (VGKCc-Ab) encephalitis is an immunotherapy-responsive syndrome usually associated with causative antibodies that target the leucine-rich, glioma inactivated 1 (LGI1) protein. Although it is expressed throughout the brain, LGI1 is not known to be expressed in cardiac tissue. We describe a novel neurocardiac prodrome of VGKCc-Ab/LGI1-en...

There is emerging evidence of a greatly increased risk of homicide, serious violence and suicide during the first episode of psychosis (FEP), which increases if there is a long duration of untreated psychosis. The period before the emergence of frank psychotic illness (the prodrome) has also been shown to be a period of increased risk. The finding of increased danger associated with the FEP has...