objective: to evaluate the potentiality of ovcar–3 cell line of ovarian adenocarcinoma as a xenograft model for ovarian adenocarcinoma in nude mice. materials and methods: the cell line isolated from advanced human ovarian adenocarcinoma, were inoculated to eight nude mice and two months later. established tumors were transferred to pathology laboratory to be prepared by h&e; staining and immun...

Gastric signet ring cell carcinoma (GSRCC) is an important histological type of gastric cancer. Its biological and clinical particularities distinguish it from other cancers in ways that require tailored management decision-making. This short review provides overview what known about this prevalent entity, highlights recent developments the research surrounding GSRCC, covers microbiome, immunol...

Breast cancer is the most prevalent disease for women. With advances in breast screening, cancers are now diagnosed early stages. knowledge of different subtypes and their behavior, treatment has become more individualized. Radiation therapy as one mainstays also been evolving. This review attempts to provide a summary influential clinical studies that have driven technological radiation early-...

Cancer is the one of most prevalent and leading causes of death in the world. Current ad­vancements in technology improve the understanding of the pathogenesis and pathology of cancers. But, due to enlarging mortality rates, poor prognosis, and lacunae in clinical early predictive biomarkers provide an important momentum to investigate novel early diagnos­tic/prognostic markers and spec...

background: previous studies indicate a high incidence of digestive cancers along southern parts of caspian sea including ma­zandaran province. the present study was conducted to further investigate time to occurrence, age distribution and pos­sible risks associated with the incidence time of digestive cancers in the above regions. methods: for this purpose the data of digestive cancer incidenc...

conclusions most patients are referred for restaging and demonstrate evidence of regional or distant metastasis with significant value for further treatment planning. providing insurance coverage and familiarizing referring physicians about appropriate indications of this relatively new diagnostic modality will be to the best interest of head and neck cancer patients in long term. methods we re...

xx Signed statement xxv Acknowledgements xxvi

BACKGROUND The aim of this study was to model the geographical variation in incidence and risk factors of seven prevalent cancers in Iran. METHODS The data for cancers of esophagus, stomach, bladder, colorectal, lung, prostate, and female breast along with their risk factors in all 30 provinces of Iran for the year 2007 were included into study. Smoking, overweight, inadequate consumption of ...