BACKGROUND Hepatitis C virus (HCV) accounts for 90% of post-transfusion hepatitis. In Uganda, there has been limited research of prevalence of HCV among sickle cell anaemia (SS) patients, a group at risk for multiple transfusions. OBJECTIVES To establish prevalence of HCV infection and determine whether blood transfusion increases risk among SS patients. METHODS 244 SS patients aged 1-18 ye...

We analyzed 77 consecutive hepatitis C antibody positive patients to compare the history, laboratory data and histological features of community acquired (CA) and post-transfusion (PT) hepatitis C. Forty-six patients had "CA" and 31 "PT" hepatitis C. Mean age in both groups was same (45.67 vs 46 years). Male to female ratio was 2:1 in the CA group and 1:2.4 in the PT group. Mean duration betwee...

The etiological agent of most cases of post-transfusion hepatitis and a variable proportion of sporadic non-A, non-B hepatitis was discovered in 1989, by recombinant cDNA immunoscreening of serum from a chimpanzee chronicaIIy infected with a contaminated human factor VIII concentrate (Choo et al., 1989). The agent was termed hepatitis C virus (HCV). It is a positive-strand RNA virus distantly r...

background and aims: recently, a novel dna virus was isolated from the serum of a patient with post-transfusion non a-g hepatitis and named tt virus. the aim of this study was to determine the prevalence tt virus among cirrhotic patients due to hepatitis b & c in infection ahwaz. methods: the prevalence of ttv infection was studied in 41 patients with liver cirrhosis. ttv dna was detected by se...

Various methods have been employed to reduce hepatitis B infections among patients and staff at high risk. Routine screening tests of all blood donors for hepatitis B surface antigen has reduced post-transfusion hepatitis B. After a control and prevention programme was instituted hepatitis B cross-infection was eliminated from haemodialysis units in Britain. Prophylaxis with specific immunoglob...

This is the first paper in which it was stated that Australia antigen (Au) was the hepatitis virus. This subsequently led to the identification of the hepatitis B virus (HBV), the development of methods for the diagnosis of hepatitis B, the prevention of post-transfusion hepatitis, the control of hepatitis in high risk environments, a vaccine against hepatitis B, and the recognition of the role...

Various methods have been employed to reduce hepatitis B infections among patients and staff at high risk. Routine screening tests of all blood donors for hepatitis B surface antigen has reduced post-transfusion hepatitis B. After a control and prevention programme was instituted hepatitis B cross-infection was eliminated from haemodialysis units in Britain. Prophylaxis with specific immunoglob...

Madam, Identification of hepatitis C virus (HCV) as a major causative organism of non-A, non-B hepatitis (NANBH) in the late 1980’s and the development of a screening test has led to the introduction of routine tests for antibodies to HCV in 1991 in the U. K. and U.S.A. In Pakistan, apart from few voluntary blood bank services who have incorporated anti-HCV screening in 1994, majority of blood ...