نتایج جستجو برای: piroctone olamine

تعداد نتایج: 105  

Journal: :European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 2016
B Hossin K Rizi S Murdan

We hypothesised that Hansen Solubility Parameters (HSPs) can be used to predict drug-nail affinities. Our aims were to: (i) determine the HSPs (δD, δP, δH) of the nail plate, the hoof membrane (a model for the nail plate), and of the drugs terbinafine HCl, amorolfine HCl, ciclopirox olamine and efinaconazole, by measuring their swelling/solubility in organic liquids, (ii) predict nail-drug inte...

Journal: :Cancer research 2011
Siyuan Song Tania Christova Stephen Perusini Solmaz Alizadeh Ren-Yue Bao Bryan W Miller Rose Hurren Yulia Jitkova Marcela Gronda Methvin Isaac Babu Joseph Ratheesh Subramaniam Ahmed Aman Anh Chau Donna E Hogge Scott J Weir James Kasper Aaron D Schimmer Rima Al-awar Jeff L Wrana Liliana Attisano

Excessive signaling from the Wnt pathway is associated with numerous human cancers. Using a high throughput screen designed to detect inhibitors of Wnt/β-catenin signaling, we identified a series of acyl hydrazones that act downstream of the β-catenin destruction complex to inhibit both Wnt-induced and cancer-associated constitutive Wnt signaling via destabilization of β-catenin. We found that ...

2016
P. CHOUHAN

The objective of the present study was to design and develop a microemulsion based transungual drug delivery formulation of ciclopirox olamine using colloidal carrier for treatment of onychomycosis. Capmul PG8 was selected as oil phase due to the high solubility of ciclopirox in it as compared to other oils and Cremophor EL and Transcutol P were used as surfactant and cosurfactant respectively....

Journal: :International Journal of Engineering and Technology 2017

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