نتایج جستجو برای: peroxisomes

تعداد نتایج: 2526  

Journal: :Molecular biology of the cell 2007
Taras Y Nazarko Andriy S Polupanov Ravi R Manjithaya Suresh Subramani Andriy A Sibirny

Sterol glucosyltransferase, Ugt51/Atg26, is essential for both micropexophagy and macropexophagy of methanol-induced peroxisomes in Pichia pastoris. However, the role of this protein in pexophagy in other yeast remained unclear. We show that oleate- and amine-induced peroxisomes in Yarrowia lipolytica are degraded by Atg26-independent macropexophagy. Surprisingly, Atg26 was also not essential f...

2014
Han Nim Lee Jimi Kim Taijoon Chung

Peroxisomes play a critical role in many metabolic pathways during the plant life cycle. It has been proposed that the transition between different types of peroxisomes involves the degradation of obsolete peroxisomal enzymes via proteolytic activities in the peroxisome matrix, the cytosol, or the vacuole. Forward and reverse genetic studies recently provided evidence for autophagic degradation...

Journal: :The Journal of biological chemistry 1999
J B Barroso F J Corpas A Carreras L M Sandalio R Valderrama J M Palma J A Lupiáñez L A del Río

The presence of nitric-oxide synthase (NOS) in peroxisomes from leaves of pea plants (Pisum sativum L.) was studied. Plant organelles were purified by differential and sucrose density gradient centrifugation. In purified intact peroxisomes a Ca(2+)-dependent NOS activity of 5.61 nmol of L-[(3)H]citrulline mg(-1) protein min(-1) was measured while no activity was detected in mitochondria. The pe...

2015
Alison M. Motley Paul C. Galvin Lakhan Ekal James M. Nuttall Ewald H. Hettema

A recent model for peroxisome biogenesis postulates that peroxisomes form de novo continuously in wild-type cells by heterotypic fusion of endoplasmic reticulum-derived vesicles containing distinct sets of peroxisomal membrane proteins. This model proposes a role in vesicle fusion for the Pex1/Pex6 complex, which has an established role in matrix protein import. The growth and division model pr...

2014
Marten Veenhuis Ida J. van der Klei

We have evaluated the current knowledge on peroxisome proliferation in yeast. In wild-type cells, peroxisomes multiply predominantly by fission at conditions that require peroxisome function(s) for growth. In cells that lack peroxisomes, for instance in pex3 and pex19 mutants or in mutants that display inheritance defects, peroxisomes may form de novo. We propose a novel machinery for the de no...

2017
Deirdre Fahy Marwa N. M. E. Sanad Kerstin Duscha Madison Lyons Fuquan Liu Peter Bozhkov Hans-Henning Kunz Jianping Hu H. Ekkehard Neuhaus Patrick G. Steel Andrei Smertenko

Plant peroxisomes maintain a plethora of key life processes including fatty acid β-oxidation, photorespiration, synthesis of hormones, and homeostasis of reactive oxygen species (ROS). Abundance of peroxisomes in cells is dynamic; however mechanisms controlling peroxisome proliferation remain poorly understood because measuring peroxisome abundance is technically challenging. Counting peroxisom...

2002
PAUL B. LAZAROW

Peroxisomes were purified by differential and equilibrium density centrifugation from the livers of rats treated with clofibrate to enhance their peroxisomal system of fatty acid oxidation. These purified peroxisomes were tested for the presence of crotonase, /3-hydroxybutyryl-CoA dehydrogenase and thiolase using spectroscopic techniques that utilize the characteristic absorption bands of the a...

Journal: :Journal of Cell Biology 2005

Journal: :Journal of experimental botany 2002
Luis A del Río F Javier Corpas Luisa M Sandalio José M Palma Manuel Gómez Juan B Barroso

Peroxisomes are subcellular organelles with an essentially oxidative type of metabolism. Like chloroplasts and mitochondria, plant peroxisomes also produce superoxide radicals (O2*(-)) and there are, at least, two sites of superoxide generation: one in the organelle matrix, the generating system being xanthine oxidase, and another site in the peroxisomal membranes dependent on NAD(P)H. In perox...

Journal: :The Journal of Cell Biology 2005
Rabiya S. Tuma

Yeast cells are known to actively partition organelles between the mother and bud during division. Mitochondria, for example, are subjected to both retention and ordered movement to ensure that a proper fraction of the organelles end up in each cell after cytokinesis. In the case of peroxisomes, researchers knew that a subset of the organelles moved into the bud in a myosin-dependent manner, bu...

نمودار تعداد نتایج جستجو در هر سال

با کلیک روی نمودار نتایج را به سال انتشار فیلتر کنید