Introduction: Dental Cone beam CT (CBCT) is an imaging modality which has emerged as a 3D imaging modality of choice for osseous structures in the maxillofacial region. With increased usage of CBCT imaging for diagnosis and treatment planning, it is imperative that stringent dose assessments must be performed for dose estimation to safeguard both the patients and operating staf...

Blood levels of cefazolin and cephalothin were determined in two separate crossover studies in 20 healthy male adults, each after intravenous and intramuscular administration. Pharmacokinetic parameters were calculated from the intravenous data based upon a two-compartment open model. The rate constants controlling the distribution between the central and peripheral compartments, the overall el...

Background: In radiation therapy, peripheral dose or the dose outside the radiotherapy field, is important when anatomical structures with very low dose tolerances are involved. One of these critical organs in pelvic irradiation is testis. The amount of radiation delivered to the testes in radiotherapy must be kept as small as possible, consistent with the limit dose of this organ. The threshol...

Background: Given the importance of scattered and low doses in secondary cancer caused by radiation treatment, the point dose of critical organs, which were not subjected to radiation treatment in breast cancer radiotherapy, was measured.Objective: The purpose of this study is to evaluate the peripheral dose in two techniques of breast cancer radiotherapy with two energies. Methods: Eight diff...

introduction:the use of beta emitters is one of the effective methods for palliation of bone metastasis. the risk of normal tissue toxicity should be evaluated in the bone pain palliation treatment. methods: in this study, the monte carlo simulation code mcnpx was used for simulation a bone phantom model consisted of bone marrow, bone and soft tissue. specific absorbed fractions were calculated...

The radial distribution of dose about the path of a heavy ion, principally from delta rays, is one of the central contributions of atomic physics to the systematization of high LET radiation effects in condensed matter, whether the detection arises in chemical, physical, or biological systems. In addition to the radial distribution of dose, we require knowledge of the response of the system to ...

Flattening filter-free (FFF) beams produce higher dose rates. Combined with compensator-based intensity modulated radiotherapy (IMRT) techniques, the dose delivery for each beam can be much shorter compared to the flattened beam MLC-based or flattened beam compensator-based IMRT. This 'snap shot' IMRT delivery is beneficial to patients for tumor motion management. Due to softer energy, superfic...

Evaluation of drug distribution into peripheral tissues is of considerable importance in pharmacokinetic analysis, especially for drugs whose sites of action are in the tissue pool. The tendency of drugs to distribute in peripheral tissues has been described in terms of volumes of distribution (Vd),' distribution or intercompartmental clearance (cLd),2*3 and mean residence (MRT,) and mean trans...