Objective: To investigate the effects of Buyang Huanwu Decoction on endoplasmic reticulum stress-autophagic response and expression GADD34 in ischemic penumbra mice with CIRI. Methods: The were randomly divided into sham operation group, model group low-, medium-, high-dosage groups. treated by gavage for 7 days before modeling 24 hours after modeling. CIRI was established ...

Introduction: In radiotherapy, treatment planning methods are evaluating and transforming every day, so precision in calculation and determination of dose delivery process is performing more important role in radiotherapy than past. In modern radiotherapy treatments, deramatically increase of small fields utilization, causes the polymeric gels has known as the most reliable dos...

BACKGROUND AND PURPOSE The penumbra of ischemic stroke consists of hypoperfused, but not irreversibly damaged, tissue surrounding the ischemic core. The purpose of this study was to determine viability thresholds in the ischemic penumbra, defined as the perfusion/diffusion mismatch in hyperacute stroke, by the use of diffusion- and perfusion-weighted MRI (DWI and PWI, respectively). METHODS D...

The ability to identify metabolically active and potentially salvageable ischaemic penumbra is crucial for improving treatment decisions in acute stroke patients. Our solution involves two complementary novel MRI techniques (Glasgow Oxygen Level Dependant (GOLD) Metabolic Imaging), which when combined with a perfluorocarbon (PFC) based oxygen carrier and hyperoxia can identify penumbra due to d...

After stroke, penumbral salvage determines clinical recovery. However, the rescued penumbra may be affected by selective neuronal loss, as documented both histopathologically in animals and using the validated in vivo positron emission tomography marker C-flumazenil in humans. However, whether the non-infarcted penumbra is capable of neuronal activation, and how selective neuronal loss may inte...

Background In patients with acute ischemic stroke, minimizing the time to revascularization can minimize neuronal death. First‐pass effect (FPE), defined as successful or complete of an occluded target vessel 1 pass a mechanical thrombectomy device(s), reduces revascularization. The objective this study was determine FPE rate, compare cases in which versus not achieved, and predictors good func...

Desde la segunda mitad del siglo XX, los proyectos de modernización en el occidente México intensificaron modificación paisaje con infraestructura para reproducción especies. En este fotoensayo rastreo movilidad una ellas, peces. Específicamente exploro figura pez ciego como narrativa modernidad que provee imagen penumbra. Si es un proyecto situado brinda luces, sugiero penumbra peces zona inte...

After stroke, penumbral salvage determines clinical recovery. However, the rescued penumbra may be affected by selective neuronal loss, as documented both histopathologically in animals and using the validated in vivo positron emission tomography marker (11)C-flumazenil in humans. However, whether the non-infarcted penumbra is capable of neuronal activation, and how selective neuronal loss may ...

Tissue sodium concentration increases in irreversibly damaged (core) tissue following ischemic stroke and can potentially help to differentiate the core from the adjacent hypoperfused but viable penumbra. To test this, multinuclear hydrogen-1/sodium-23 magnetic resonance imaging (MRI) was used to measure the changing sodium signal and hydrogen-apparent diffusion coefficient (ADC) in the ischemi...