background: the prevalence of food allergy is different in different parts of the world. identification of the most common food allergens is a priority in any population to provide effective preventive and curative measures.   objective: the aim of this study was to determine the most common food allergens in iranian children.   methods: one hundred and ninety children with skin, respiratory or...

Cutaneous sensitization with a food antigen before its consumption elicits the development of food allergy. Here we report the site and stage dependent roles of basophils and pro-allergic cytokines, thymic stromal lymphopoietin (TSLP) and IL-33, in a mouse model of food allergy initially sensitized cutaneously with the food antigen. Mice are epicutaneously sensitized with the food antigen ovalb...

BACKGROUND The etiology of chronic urticaria (CU) remains unknown in most patients. Possible causes in some cases include food, but the role of allergy to food antigens in patients with CU remains controversial. OBJECTIVE The aim of this study was to evaluate the association between food allergy and CU. METHODS Korean patients with CU were assessed for a previous history of food allergy tha...

Methods Seven children aged 9 months to 6.6 years (median 1.7 years) with hen’s egg allergy were performed open oral food challenge tests with boiled hen’s egg to define the threshold dose. Subjects underwent SOTI in which they intake boiled hen’s egg at home 3 days every week. The dose was increased every 1 to 2 weeks from approximately one fourth of the threshold dose to 60g. Clinical respons...

………………………………………………………………………. . 1 LIST OF ORIGINAL PAPERS …………………………………………………... . 3 ABBREVIATIONS ……………………………………………………………….. 4 DEFINITIONS AND EXPLANATIONS ……………………………………….... 5 INTRODUCTION………………………………………………………………..... 7 The Atopic March ………………………………………………............... 8 Risk factors in atopic disease ………………………………………….. 8 Prevention of atopic disease ……………………………………………10 Eczema ……………………………………...