Nail disorders are the most frequent reason for visits to podiatry clinic. Although they not a severe health problem, these types of pathologies have psychosocial impact on patients, affecting their self-esteem and leading social professional self-isolation that can cause anxiety depression. Laser therapy is considered potential treatment nail because it fast, easily applied avoids interaction ...

We present a case of a 30-year old female patient presenting with acrocyanosis and nail changes (leukonychia, onycholysis), who has been treated with valproic acid for 3 years. Acrocyanosis, listed in the group of acrosyndromes, is a painless condition, characterized by symmetrical discoloration of various shades of blue colour, localized within the hands, feet and face, often associated with h...

Nail abnormalities occur frequently in patients with psoriatic arthritis. This study of the finger nails of 46 patients with psoriatic arthritis, 100 nonpsoriatic rheumatism patients, and 100 nonpsoriatic general medical patients was designed to characterise these abnormalities with particular reference to the severity of nail pitting. The results of the study suggest: (1) Onycholysis alone in ...

Background / Objectives:Dermoscopy is a non-invasive technique that has been recognized recently as an effective tool in the diagnosis of nail diseases, including psoriasis. The aim this study was to clarify specific dermoscopic features psoriasis and identify those are correlated with disease severity. Methods: We conducted prospective over 18 months. Fifty patients followed for involvement we...

Valproic acid is an effective, frequently used anticonvulsant drug. Typical adverse effects include weight gain, hair loss, and nausea. Hyperpigmentation, onycholysis, and onychomadesis are nail changes that can be seen after valproic acid use. Changes occur at the distal and proximal portions of the nail bed in onycholysis and onychomadesis, respectively. Onychomadesis is a very rare disease o...

The clinical characteristics of nail changes in seven patients receiving taxane-containing chemotherapy are described. They include nail pigmentation, subungual hematoma, Beau's lines and onycholysis and subungual suppuration. The incidence of such changes (ranging from 0% to 44%) is reviewed from a Medline search of the literature.