MICROBIOLOGY. For the article ‘‘A Mr 34,000 proinflammatory outer membrane protein (oipA) of Helicobacter pylori’’ by Yoshio Yamaoka, Dong H. Kwon, and David Y. Graham, which appeared in number 13, June, 20, 2000, of Proc. Natl. Acad. Sci. USA (97, 7533–7538), the authors note the following correction. The sequence of the HP0638 gene was incorrect as published. The sequence published was 59-GCT...

helicobacter pylori has been strongly associated with peptic ulcer diseases, chronic gastritis, ulcers, and reported as a risk factor for gastric cancer, too. the vaculating cytotoxin (vaca), the cytotoxin associated genes (caga), the induced by contact with epithelium factor antigen (icea gene), blood adhesion binding antigen (baba2), and outer membrane protein oipa have been described as diff...

The aims of our work were to determine the presence of the cag pathogenicity-island (cag PAI) and other virulence genes of Helicobacter pylori recovered from patients with gastritis and peptic ulcer, and to investigate the correlation of these virulence genes with clinical outcome. The presence of the cagA, the promoter regions of cagA, cagE, cagT, and the left end of cag-PAI (LEC), cag right j...

helicobacter pylori infection is a common gastrointestinal infection that can cause pathological effects, increase oxidative stress and induce an inflammatory response in gastric mucosa. inflammatory aspects may prompt the production of radical oxygen substance (ros) which may damage cells and release 8-hydroxydyoxyguanosine (8-ohdg) to serum. in this study, we evaluate the prevalence of h. pyl...

The incidence of gastrointestinal diseases and in particular gastric cancer (GC) is high worldwide. Over the last few years, numerous studies have speculated that Helicobacter pylori (H. pylori) and Epstein-Barr virus (EBV) can be correlated with gastric cancerogenesis. Virulence factors of H. pylori can contribute to the variability of clinical outcomes: among the most important virulence fact...