نتایج جستجو برای: mrna transfection
تعداد نتایج: 170520 فیلتر نتایج به سال:
Geneand cell-based therapies are promising strategies for the treatment of degenerative retinal diseases such as age-related macular degeneration (AMD), Stargardt disease and Retinitis Pigmentosa. Cellular engineering before transplantation may allow the delivery of cellular factors that can promote functional improvements such as increased engraftment or survival of transplanted cells. A curre...
Background & aims: Hemophilia B is caused by either functional deficiency or lack of the human coagulation factor IX (hFIX). The current protein-based therapy with plasma-derived proteins increases, the risk of blood-borne pathogens transmission. Therefore, replacement therapy with recombinant hFIX (rhFIX) is an attractive alternative to plasma derived hFIX concentrates. In order to express and...
Background: Electroporation is a valuable tool for small interfering RNA (siRNA) delivery into cells because it efficiently transforms a wide variety of cell types. Since electroporation condition for each cell type must be determined experimentally, this study presents an optimal electroporation strategy to reproducibly and efficiently transfect MDA-MB 468 human breast cancer cell with siRNA. ...
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