Abstract Background There is a growing consensus across stakeholders on the value of patient preference (PP) studies, as recognized by European Medicines Agency and Network for Health Technology Assessment. This study aimed to develop PP survey quantitatively evaluate which characteristics are most important inflammatory bowel disease (IBD) patients, so that results can inform medicinal product...

The antioxidant properties of various fractions of a methanolic extract obtained from the aerial parts of Verbascum macrurum have been determined by monitoring their capacity to scavenge the stable free-radical DPPH. They were also evaluated as natural preservatives against oxidative rancidity using the accelerated Rancimat method. Their activities expressed as protection factor (PF(r)) indicat...

Phlomis bruguieri is a native plant in Iran, which deserves phytochemical study. The aim of this study was evaluation its iridoid contents along with antioxidant capacity. Aerial parts the material were extracted methanol and applied on repeated normal column chromatography using hexane: chloroform (70:30), chloroform: (90:10), (100%). fraction eluted (100%) containing polar glycosides selected...

stachys lavandulifolia vahl is an herbaceous wild plant native to iran which is traditionally used in iranian folk medicine as a mild sedative tea for reducing anxiety and for treatment of gastrointestinal disorders. our previous study on ethyl acetate extract of s. lavandulifolia proved anti-anxiolytic activity and so the present study was designed to determine chemical components of this biol...

Background: Marine seaweeds synthesize different metabolites with various biological activities, including antimicrobial effects. Objectives: The main object of this study was to fractionate the seaweed Padina australis and analyze activities these fractions isolate bioactive compounds. Methods: collected from Persian Gulf extracted by maceration methanol-ethyl acetate solvent. extract evaporat...

Forage-based nutrients constitute the main forage value of grass. Elymus nutans Griseb possesses a wide ecological adaptability, enhanced crude protein content, good palatability, and excellent genes. Herein, employing medium- (MPLC) high-pressure liquid chromatography (HPLC), along with online HPLC-DPPH (OHD)-based identification, two primary radical scavenging compounds were extracted identif...

Context Some Ajuga L. (Lamiaceae) species are traditionally used for the treatment of malaria, as well as fever, which is a common symptom of many parasitic diseases. Objective In the continuation of our studies on the identification of antiprotozoal secondary metabolites of Turkish Lamiaceae species, we have investigated the aerial parts of Ajuga laxmannii. Materials and methods The aerial par...

The problem of context has a long tradition in different areas of artificial intelligence (AI). However, formalizing context has been widely discussed only since the late 80s, when J. McCarthy argued that formalizing context was a crucial step toward the solution of the problem of generality. Since then, two main formalizations have been proposed in AI: Propositional Logic of Context (PLC) and ...

INTRODUCTION A previous study showed the unique character of Nigerian red propolis from Rivers State, Nigeria (RSN), with regards to chemical composition and activity against Trypanosoma brucei in comparison with other African propolis. OBJECTIVE To carry out fractionation and biological testing of Nigerian propolis in order to isolate compounds with anti-trypanosomal activity. To compare the...