electromagnetic field (emf) radiation affects cellular and brain chemistry and function, resulting in deleterious effects such as free radicals formation, impaired dna repair, reduced melatonin and blood brain barrier protection, and defects on learning and memory and other higher brain functions. in this paper the effects of low frequency emf of 50- and 217 hz, ranges often associated with com...

Objective: The present study investigated possible neuroprotective effects of ethanolic extract of Tiliacora triandra leaf against cerebral ischemic-reperfusion injury in mice. Materials and Methods: Forty male Institute of Cancer Research (ICR) mice were randomly divided into five groups: (1) Sham + 10% Tween 80, (2) bilateral common carotid artery occlu...

Investigation of the Role L-Arginine and L-NAME in Dorsal Hippocampus on Anxiety, Depression Brain Level BDNF after Stress Male Mice

Sleep plays a crucial role in maintaining brain health. Insufficient sleep leads to an enhanced permeability of the blood–brain barrier and development diseases small cerebral vessels. In this study, we discuss possibility detecting changes electrical activity associated with deficit, using extended detrended fluctuation analysis (EDFA). We apply approach electroencephalograms (EEG) mice identi...

dementia is one of the age related mental problems and a characteristic symptom of various neurodegenerative disorders including alzheimer’s disease. desmodium gangeticum dc. (leguminosae) is widely used in ayurveda for treating various neurological disorders. in the present study, the effectiveness of aqueous extract of d. gangeticum in attenuating scopolamine-induced amnesia in mice was inves...

Depression is a common and debilitating condition for which effective treatments are needed. Lepidium meyenii Walp (Maca) plant with potential medicinal effects in treating depression. Recently, there has been growing interest plant-derived extracellular vesicles (EVs) due to their low toxicity ability transport human cells. Targeting the gut–brain axis, novel strategy depression management, ma...

Immune checkpoint inhibitors have great potential for the treatment of gliomas; however, their therapeutic efficacy has been partially limited by inability to efficiently cross blood–brain barrier (BBB). The objective this study was evaluate capability focused-ultrasound-mediated intranasal brain drug delivery (FUSIN) in achieving locally enhanced anti-programmed cell death-ligand 1 antibody (a...

Background: The oxidant-antioxidants balance in the living organism is constantly challenged by internal and external pressures. Maidenhair or Adiantum capillus-veneris (Acv) is rich in bioactive compounds with antioxidant effects.  Objectives: The present study aimed at investigating the effect of Acv hydroalcoholic extract on the oxidative stress rate of blood and brain of mice in the depres...

introduction: celastrus paniculatus seed oil, commonly known as malkangni or jyotishmati, was in use from time immemorial to treat brain related disorders. celastrus paniculatus seed oil has significant antidepressant-like activity in chronic unpredictable stressed mice. the present study was undertaken to evaluate the antidepressant-like effect of celastrus paniculatus seed oil in unstressed m...