نتایج جستجو برای: maternal serum screening tests

تعداد نتایج: 919918  

Adiban, Farzaneh, Amidi, Salomeh, Balavayeh, Payam, Delshad, Saeed, Helat Abadi, Mahboubeh, Jamali, Soudabeh, Modaresi, Mohammad Hossein, Navidpour, Fariba, Rafi, Neda, Saadati, Pourandokht, Savad, Shahram, Taheri Amin, Mohammad Mehdi, Younesi, Sarang,

Introduction: Prenatal maternal serum AFP screening tests have some inherent false positive and false negative results. For NTDs Screening test (FTS) false positive rate (FPR) is about 1% and false negative rate (FNR) is 20%. A false positive result encourages by Anomaly scan and invasive diagnostic procedures (that poses lots of stress on women, too), while a false negative result lead to a N...

Journal: :international journal of molecular and cellular medicine 0
mohammad kazemi department of genetics and molecular biology, school of medicine, isfahan university of medical sciences, isfahan, iran.سازمان اصلی تایید شده: دانشگاه علوم پزشکی اصفهان (isfahan university of medical sciences)سازمان های دیگر: pediatric inherited diseases research center, re search institute for primordial prevention of non- pediatric inherited diseases research center, re search institute for primordial prevention of non-communicable disease, isfahan university of medical sciences, isfahan, iran. mansoor salehi medical genetic center of genome, isfahan, iran.سازمان های دیگر: pediatric inherited diseases research center, re

down syndrome (ds) is a birth defect with huge medical and social costs, caused by trisomy of whole or part of chromosome 21. it is the most prevalent genetic disease worldwide and the common genetic cause of intellectual disabilities appearing in about 1 in 400-1500 newborns. although the syndrome had been described thousands of years before, it was named after john langdon down who described ...

Journal: :Revista brasileira de ginecologia e obstetricia : revista da Federacao Brasileira das Sociedades de Ginecologia e Obstetricia 2013
Melody Menezes Simon Meagher Fabricio da Silva Costa

Technology in the prenatal setting is advancing at an exceptional rate, and these advancements will likely result in major changes to current pregnancy screening and testing paradigms. In Australia, prenatal testing is increasingly becoming a routine part of antenatal care and pregnant women are offered an assortment of screening and diagnostic tests, which give them information about their fet...

Journal: :Prenatal diagnosis 2010
Leona C Y Poon Violeta Stratieva Silvia Piras Solmaz Piri Kypros H Nicolaides

OBJECTIVE To explore if the addition of pregnancy-associated plasma protein-A (PAPP-A) to maternal factors and biophysical markers yields a significant improvement in the detection of hypertensive disorders before the clinical onset of disease. METHODS Prospective screening study for early preeclampsia (PE), late PE and gestational hypertension (GH) in women attending their first hospital vis...

Journal: :Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology 2003
K H Nicolaides

Chromosomal abnormalities are major causes of perinatal death and childhood handicap. Consequently, the detection of chromosomal disorders constitutes the most frequent indication for invasive prenatal diagnosis. However, invasive testing, by amniocentesis, chorionic villus sampling (CVS) or cordocentesis, is associated with a risk of miscarriage of about 1% and therefore these tests are carrie...

Journal: :Acta paediatrica 2011
Mariane Rix Peter Laurberg Christina Porzig Søren Risom Kristensen

UNLABELLED Elevated thyroid-stimulating hormone (TSH) was discovered by routine neonatal screening in a newborn with no clinical symptoms. Thyroid function tests were repeated and confirmed a high TSH value but normal total thyroxine (T4) and triiodothyronine (T3). However, the mother also had elevated serum TSH with normal levels of T4 and T3. The results suggested a transmitted maternal inter...

Journal: :Prenatal diagnosis 1998
T Beazoglou D Heffley J Kyriopoulos A Vintzileos P Benn

Maternal serum screening for Down syndrome involves biochemical tests such as alpha-fetoprotein (alpha FP), human chorionic gonadotrophin (hCG) and unconjugated oestriol (uE3), either alone or in combination, that have variable detection and false-positive rates. Choosing a screening protocol requires a trade-off between a desired detection rate and an acceptable false-positive rate. Selecting ...

2018
Farzaneh Broumand Shaker Salari Lak Farhad Nemati Atefeh Mazidi

Background Hypertensive disorders are common during pregnancy, and are among 3 important causes of maternal death. Preeclampsia occurs in 3 to 5% of pregnancies. Early diagnosis of this disorder can lead to better pregnancy outcomes. Objective The aim of this study was to determine the relationship between inhibin A serum levels during second stage pregnancy screening tests, and incidence and...

Journal: :Journal of the Chinese Medical Association : JCMA 2005
Ming-Jie Yang

BACKGROUND The aim of this study was to evaluate the interrelationships between maternal serum leptin level and body mass index (BMI) at different gestational ages or during the whole pregnancy. METHODS A total of 374 blood samples were obtained from 114 pregnant women when they visited the prenatal clinic for registration, Down syndrome screening test, 50 g oral glucose challenge test, hepat...

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