objective(s) the objective of this study was to prepare, characterize and evaluate the nanoliposomes containing safranal as a natural sunscreen and moisturizer factor. materials and methods the experimental formulations included homosalate reference, nanoliposomes containing 0.25, 0.5, 1, 2, 4 and 8% safranal and empty liposomes. the liposomes were prepared using fusion method and homogenizatio...

Liposomes, as biocompatible and safe nanocarriers with easily modified surfaces, can be well used in the field of antitumor. Their targeting properties have contributed to reduction drug dosage non-target cell toxicity. To further exploit liposomes, passive active liposomes physicochemical been constructed by surface modification. This paper summarizes mechanisms action different types targeted...

Liposomes are sphere-shaped vesicles made up of one or more bilayers phospholipids. The ability delayed to transport medications, vaccines, diagnostic specialists, and other bioactive operators has accelerated development in the liposomal drug delivery system. system's pharmacyelements pharmacokinetics properties have been altered, resulting a higher therapeutic index lower overall toxicity. Th...

The purpose of this study was to optimize a method for the encapsulation of P5 peptide, a new designed peptide containing MHC class I epitopes from rat HER2/neu protein, into liposomes as an approach for breast cancer vaccine formulation. The efficiency of liposomal encapsulation of peptides is generally low and development of an optimized method to increase encapsulation efficiency is a big ch...

Background and aim: Efficacy of vaccines is mainly depending on the type of adjuvant used. Efficacy trials of first generation vaccine against leishmaniasis showed a limited efficacy due to lack of an appropriate adjuvant. The objective of this study was to investigate whether positively charged liposomes containing ALM could induce Th1 type immune response in susceptible Balb/c mice.Mate...

The aim of current study was to investigate the effect of Brij decoration of liposomes on in vitro and in vivo characteristics of the nanocarriers. Two hydrophilic Brij surfactants (Brij 35 and Brij 78) with almost similar molecular weight but differing in acyl chain were incorporated into liposomal bilayers at two percentages (5% and 10%). Conventional liposomes (CL) containing egg phosphatidy...

introduction : the encapsulation of nutraceuticals in lipid based carriers, such as liposomes, can lead to increasing of bio-active ingredients bioavailability and controlled release, maintaining their stability in different environmental conditions and increasing solubility of hydrophobic active ingredients in aqueous conditions. food grade liposomes are being increasingly used in food industr...

background the increased incidence of fungal resistance has necessitated the need to search for new antifungal agents. objective the main objectives of the present study were to investigate the effectiveness of the essential oil of eucalyptus camaldulensis on dermatophytes growth and to formulate and characterize a liposomal gel loaded with the essential oil. materials and methods the essential...

the purpose of this study was to optimize a method for the encapsulation of p5 peptide, a new designed peptide containing mhc class i epitopes from rat her2/neu protein, into liposomes as an approach for breast cancer vaccine formulation. the efficiency of liposomal encapsulation of peptides is generally low and development of an optimized method to increase encapsulation efficiency is a big ch...

superoxide dismutase (sod) is an important antioxidant that protects many types of cells from the free radical damage. one of the possible ways for the use of sod is its incorporation in liposomes. the aim of this study was to investigate the effect of cationic phospholipids on the entrapment of human erythrocyte superoxide dismutase (cu/zn sod) in liposomes. also, in the present study, we exam...