Background: EMLA cream is a eutectic mixture of Lidocaine and Prilocaine used to induce local anesthesia for dermatological procedures. Objective: This study was designed to evaluate the efficacy of EMLA cream in reducing the pain of intralesional injection of steroid in patients with alopecia areata. Patients and Methods: This study was carried out on 27 alopecia areata patients. The injection...

OBJECTIVES To determine the efficacy and safety of 'healer' cream as monotherapy in the treatment of acute and chronic anal fissure. STUDY DESIGN A prospective, randomized, single blinded, comparative trial. METHODS Sixty patients suffering from anal fissure were included in the study. Patients were randomly divided into three groups: group A: treated with 'healer' local cream application 3...

abstract background the present randomized clinical trial evaluated the efficacy of a topical lidocaine-prilocaine cream (emla) to relief pain during spinal puncture in pediatric oncology patients. materials and methods sixty patients with malignancy candidate for spinal puncture were selected for this study. the patients were randomly allocated to two groups. group a had topical emla cream and...

BACKGROUND Pain of circumcision is only partially relieved by single modalities, such as penile nerve block, lidocaine-prilocaine cream, and sucrose pacifiers. OBJECTIVE To assess the effectiveness of a combination of interventions on the pain response of infants undergoing circumcision. METHODS Cohort study. Group 1 included infants circumcised using the Mogen clamp and combined analgesics...

Elsisi GH, Kaló Z, Eldessouki R, Elmahdawy MD, Saad A, Ragab S, Elshalakani A, Abaza. Recommendations for Reporting Pharmacoeconomic Evaluations in Egypt. Value in Health RI 2013:2;319-327. Fig. 1: Decision tree model ECONOMIC EVALUATION OF LIDOCAINE/TETRACAINE PATCH VERSUS LIDOCAINE/PRILOCAINE CREAM FOR TOPICAL ANAESTHESIA BEFORE VASCULAR ACCESS IN EGYPT ElSisi GH1* , Mohamed Abdallah H1, Elma...

Abstract Background The present randomized clinical trial evaluated the efficacy of a topical lidocaine-prilocaine cream (EMLA) to relief pain during spinal puncture in pediatric oncology patients. Materials and Methods Sixty patients with malignancy candidate for spinal puncture were selected for this study. The patients were randomly allocated to two groups. Group A had topical EMLA cream...

In our experience patients undergoing circumcision are mostly concerned about pain and penile appearances. We conducted a prospective randomized trial to assess the benefits of a new disposable circumcision suture device (DCSD). A total of 942 patients were equally divided into three groups (conventional circumcision, Shang ring and disposable suture device group). Patients in the DCSD group we...

PURPOSE This study compared the efficacy of commonly used topical anesthetics using an objective measuring scale. METHODS The following were tested: 5% EMLA cream, 10% cocaine, 10% lidocaine, 10% benzocaine, 1% dyclonine, and a placebo. A special instrument was designed to serve the purpose of pressure application on the gingiva to obtain a threshold discomfort level in grams before and after...

Main results 27 trials were included. 6 trials evaluated topical treatments (follow up of 2 d to 6 wk). Of 2 trials that compared a lidocaine patch with placebo, 1 showed no difference and 1 showed a reduction in pain with lidocaine. 2 trials showed greater pain relief with capsaicin 0.075% cream than with placebo. 2 trials comparing benzydamine cream with placebo showed no difference between g...

Postherpetic neuralgia (PHN) represents a potentially debilitating and often undertreated form of neuropathic pain that disproportionately affects vulnerable populations, including the elderly and the immunocompromised. Varicella zoster infection is almost universally prevalent, making prevention of acute herpes zoster (AHZ) infection and prompt diagnosis and aggressive management of PHN of cri...