Linkage disequilibrium (LD) is bases of genomic selection, genomic marker imputation, marker assisted selection (MAS), quantitative trait loci (QTL) mapping, parentage testing and whole genome association studies. The Particular alleles at closed loci have a tendency to be co-inherited. In linked loci this pattern leads to association between alleles in population which is known as LD. Two metr...

BACKGROUND AND METHODOLOGY Men's and women's attitudes towards the male contraceptive pill and their trust in the effective use of the male pill were investigated, as well as the associated variables of reported health behaviours, perceived self-efficacy and type of sexual relationship, using a questionnaire survey. RESULTS Although both sexes had a favourable attitude towards the male pill, ...

CONTEXT Although studies have examined U.S. pill users' patterns of discontinuation, little is known about pill discontinuation, and the effects of partner influence, among Hispanics. METHODS Follow-up data on pill use were collected from 213 predominantly Hispanic women who requested the pill in an urban family planning clinic in 2000. Logistic regression analyses were conducted to assess th...

background: despite the importance of patients’ adherence to their drug treatments for achieving desired therapeutic goals and the proven role 3-hydroxy-3-methylglutaryl coenzyme a inhibitors (statins) for the health status of patients with cardiovascular diseases, there is not enough information regarding diabetic patients’ adherence to statin therapy in developing countries. in this clinical ...

The side-effects encountered by 1,090 patients taking the oral contraceptive pill were reviewed. The main side-effects were migraine, headaches, weight gain, depression, and irregular bleeding. Reasons for changing the Pill are discussed, and recommendations are suggested for a way of monitoring patients taking the Pill. Analysis of the results show that 50 per cent of patients are happy with t...

The label on a bottle of pills says “Take one half pill daily.” A natural way to proceed is as follows: Every day, remove a pill from the bottle at random. If it is a whole pill, break it in half, take one half, and return the other half to the bottle; if it is a half pill, take it. We analyze the history of such a pill bottle.

OBJECTIVES Single-pill combination therapy (amlodipine/atorvastatin) might be more effective than double-pill therapy (amlodipine+atorvastatin) in patients with diabetes and concomitant hypertension requiring statin therapy. We compared the cost-effectiveness of a single-pill with that of double-pill for control of low density lipoprotein cholesterol (LDL-C) levels, with the ultimate goal of ca...

objective(s): the aim of the present study was to evaluate antioxidant and methyl donor effects of betaine in cerebellum following levodopa and benserazide administration in rats. materials and methods: sprague-dawley male rats were treated with levodopa (ld), betaine (bet), levodopa plus betaine (ld/bet), levodopa plus benserazide (ld/ben), levodopa plus betaine-benserazide (ld/bet-ben), and t...

A 26-year-old male presented with symptoms of acute esophageal obstruction immediately after swallowing an 800-mg ibuprofen tablet. Multiple attempts to extract the pill with a variety of traditional endoscopic retrieval devices were unsuccessful. We successfully destroyed the pill using a threaded-tip biliary stent retrieval device to drill a hole in the center of the pill, which allowed us to...