The prognosis of progressive ophthalmoplegia in patients with large-scale mitochondrial DNA deletions is highly variable and almost unpredictable. The risk to develop cardiac involvement and sudden cardiac death is strikingly high, especially in patients with Kearns-Sayre syndrome (KSS). The most typical cardiac complications of the disease are conduction defects, which usually begin with left ...

This paper reports on some of the difficulties inherent in the integration of information from heterogeneous knowledge sources (KSs). It reviews the approaches and limitations of some recent systems, and presents example problems from an attempt to integrate two KSs in the medical terminology domain.

This paper reports on some of the difficulties inherent in the integration of information from heterogeneous knowledge sources (KSs). It reviews the approaches and limitations of some recent systems, and presents example problems from an attempt to integrate two KSs in the medical terminology domain.

Although much is known about human body vibration discomfort, there is little research data on the effects of vibration on vehicle occupant drowsiness. A laboratory experimental setup has been developed. Vibration was applied to the volunteers sitting on the vehicle seat mounted on the vibration platform. Seated volunteers were exposed to a Gaussian random vibration, with 1-15 Hz frequency band...

OBJECTIVE : The objective of this study was to describe self-assessed student knowledge of female pelvic medicine (FPM) during the OBGYN clerkship. METHODS : Students at 6 sites scored their knowledge of 12 FPM topics and 4 procedures both before and after their clerkship. Analysis included Wilcoxon tests, Spearman correlation, and univariate and multivariate models. RESULTS : A total of 32...

Block Krylov subspace spectral (KSS) methods are a “best-of-both-worlds” compromise between explicit and implicit time-stepping methods for variable-coefficient PDE, in that they combine the efficiency of explicit methods and the stability of implicit methods, while also achieving spectral accuracy in space and high-order accuracy in time. Block KSS methods compute each Fourier coefficient of t...

Kearns-Sayre syndrome (KSS) is a rare mitochondrial myopathy that usually develops before 20 years of age. It demonstrates multisystemic involvement with a triad of cardinal features: progressive ophthalmoplegia, pigmentary retinopathy, and cardiac conduction abnormalities. In addition, patients might have cerebellar ataxia, a high content of protein in the cerebrospinal fluid, proximal myopath...

The 2011 KSS is a valid clinical TKA questionnaire, but with a low completion rate (42%). Adjustments, focusing on optimizing scale features, are required to improve its clinical use. The low completion rates, non-optimal scale features, lacking rules or a combination of these factors where addressed, leading to the development of the adjusted 2011 KSS (2011 KSS-A). Four-hundred-ninety-nine pri...

The task of inverting logical entailment is of central importance to the disciplines of Abductive and Inductive Logic Programming (ALP& ILP). Bottom Generalisation (BG) is a widely applied approach for Inverse Entailment (IE), but is limited to deriving single clauses from a hypothesis space restricted by Plotkin’s notion of C-derivation. Moreover, known practical applications of BG are confine...

We obtain KSS, Strichartz and certain weighted Strichartz estimate for the wave equation on (R, g), d ≥ 3, when metric g is non-trapping and approaches the Euclidean metric like 〈x〉 with ρ > 0. Using the KSS estimate, we prove almost global existence for quadratically semilinear wave equations with small initial data for ρ > 1 and d = 3. Also, we establish the Strauss conjecture when the metric...