ALL is now diagnosed and classified according to the WHO classification of neoplastic disease of hematopoietic and lymphoid tissues [2]. ALL is defined by the presence of ≥ 20% lymphoblasts in the marrow or peripheral blood. This is a change from the previous FAB classification, which required ≥ 30% blasts [3]. The relationship between ALL and lymphoblastic lymphoma remains unclear. Under the W...

Morular metaplasia has been exceptionally described in the stomach. We report the formation of morules in a case of sporadic fundic gland polyposis with low grade dysplasia in a 47 year old woman that underwent total gastrectomy. The immunophenotype of the morules was CD10, CDX2, Beta-catenin nuclear positive; p63, Ki67, chromogranin, synaptophysin, Ck20 negative. The presence of morules in a n...

Peripheral T cell lymphomas (PTCLs) form a morphologically heterogeneous group of non-Hodgkin's lymphomas that are generally considered to have immunophenotypes associated with mature T cells, usually those of helper T cells. We now describe and correlate the clinical, morphological, immunologic, and cell-kinetic findings based on the evaluation of eight tissue samples obtained at various times...

Macrophages have been confirmed to play a significant role in the behavior of human lymphomas, albeit no consistent data are so far available canine lymphomas. The present study characterizes macrophages cases nodal lymphoma and their relationship with histological grade immunophenotype. Samples from lymph nodes 25 dogs diagnosed were selected. Immunohistochemistry was used determine tumor immu...