The treatment of primary hyperlipidaemic states is reviewed. While several metabolically distinct forms of hyperlipidaemia exist, it is possible to classify patients into three groups for the purpose of therapy. Group 1 is defined as hypercholesterolaemia (due to raised levels of ,8-lipoprotein). In Group 2 the level of endogenous triglyceride is increased, with or without hypercholesterolaemia...

The treatment of primary hyperlipidaemic states is reviewed. While several metabolically distinct forms of hyperlipidaemia exist, it is possible to classify patients into three groups for the purpose of therapy. Group 1 is defined as hypercholesterolaemia (due to raised levels of ,8-lipoprotein). In Group 2 the level of endogenous triglyceride is increased, with or without hypercholesterolaemia...

Hypercholesterolaemia is an established major risk factor for coronary heart disease (CHD) in the general population. In the vast majority of studies that focused on this particular age group and carefully eliminated other confounding factors such as co-morbid conditions, hypercholesterolaemia was a risk factor for CHD in the older population. Because the prevalence of CHD increases with advanc...

The aim of the present study was to assess the effect of gestational hypercholesterolaemia on the prostaglandin-induced uterine response in late pregnant mouse uterus. Gestational hypercholesterolaemia was developed in Swiss albino mice feeding a diet (HFHC diet) containing 1.25 % cholesterol, 0.5 % sodium cholate and 15 % fat for 6 weeks before mating and continuing up to the 19th day of gesta...

358:1431–1443. 30. Weight Control and Physical Activity. Lyon: International Agency for Research on Cancer; 2002. (IARC Handbooks of Cancer Prevention, vol. 6). 31. Diet, Nutrition, and the Prevention of Chronic Diseases Report of a Joint WHO/FAO Expert Consultation. Geneva, World Health Organisation; 2003. (WHO Technical Report Series, No. 916). 32. Rao S, Porter DC, Chen X, Herliczek T, Lowe ...

OBJECTIVE To develop a population screening strategy for familial hypercholesterolaemia. DESIGN Meta-analysis of published data on total and low density lipoprotein (LDL) cholesterol in people with and without familial hypercholesterolaemia according to age. Thirteen studies reporting on 1907 cases and 16 221 controls were used in the analysis. Included studies had at least 10 cases and contr...