The bone morphogenetic protein (BMP) signaling pathway is essential during gastrulation for the generation of ventral mesoderm, which makes it a challenge to define functions for this pathway at later stages of development. We have established an approach to disrupt BMP signaling specifically in lateral mesoderm during somitogenesis, by targeting a dominant-negative BMP receptor to Lmo2+ cells ...

Snakebite is a conflict between venomous snakes and humans as well livestock considered neglected tropical disease. The present study aimed to investigate the hospital prevalence, clinical hemato-biochemical aspects of hemotoxic snakebite in bovines. overall prevalence bovines was found be 0.93%. Highest observed August month during monsoon season female with higher cases buffaloes. highest occ...

1 Dept. of Engineering and Architecture, University of Trieste, Trieste, Italy. E-mail: [email protected] 2 Department of Engineering and Architecture, University of Trieste, Trieste, Italy 3 Institute for Maternal and Child Health (IRCCS) Burlo Garofolo, UO Pediatric Hemato-Oncology, Trieste, Italy 4 Dept. of Engineering and Architecture, University of Trieste, Trieste, Ital. 5 Dept. of Engi...

A recent publication identifies npas4l as the gene defective in the well-known cloche mutant that lacks most endothelial as well as hematopoietic cells. This work poses intriguing questions as to the genetic and molecular nature of the origin of hemato-vascular lineages during early embryogenesis.

Introduction Hyperlactatemia is often associated with poor clinical outcomes. Mortality is increased when lactic acidosis with low-flow states or sepsis. For improving poor prognosis, early detection and intervention of hyperlactatemia are important. There are call for monitoring blood lactate level. However, hyperlactatemia is often associated with type II lactic acidosis in hemato-oncologic m...

1 Pediatric Infectious Disease Unit, Hôpital Universitaire des Enfants Reine Fabiola, Brussels, Belgium, 2 Service du Sang, Belgian Red Cross, Brussels, Belgium, 3 Hemato-oncology Department, Hôpital Universitaire des Enfants Reine Fabiola, Brussels, Belgium, 4 Department of Clinical Sciences, Institute of Tropical Medicine, Antwerp, Belgium, 5 Laboratory of Parasitology, Faculty of Medicine, U...