This paper describes the results of using genetic programming with bounded iteration constructs, which allow the computational complexity of the solution to be an emergent property. It is shown that such operators render the even-6-parity problem trivial, and the results of experiments with other, harder, problems that require O(n) complexity are shown. This method is contrasted with Automatica...

in this paper, first, an initial feature vector for vocal fold pathology diagnosis is proposed. then, for optimizing the initial feature vector, a genetic algorithm is proposed. some experiments are carried out for evaluating and comparing the classification accuracies which are obtained by the use of the different classifiers (ensemble of decision tree, discriminant analysis and k-nearest neig...

Herpes simplex virus (HSV)-based vectors have been used as platforms for the generation of genetic vaccines against different viruses. Some of the advantages of defective HSV-1 vectors include: (a) HSV-1 can infect most cell types, including antigen-presenting cells; (b) HSV-1 vectors have a large transgene capacity (up to 150-kbp); (c) HSV-1 vectors can be designed to cause no toxicity; (d) di...

Many measurement methods of velocity vector distributions by image processing have been developed and applied to various flows. Most of them, however, have a serious problem. The estimated velocity vectors in a flow field include some erroneous ones because of mismatching a tracer image pattern to another one. Accordingly, it is necessary to determine the erroneous vectors which exist in the es...

Viral vectors have been extensively studied due to their great transduction efficiency compared to non-viral vectors. These vectors have been used extensively in gene therapy, enabling the comprehension of, not only the advantages of these vectors, but also the limitations, such as the activation of the immune system after vector administration. Moreover, the need to control the target of the v...

The emergence of genetic engineering at the beginning of the 1970's opened the era of biomedical technologies, which aims to improve human health using genetic manipulation techniques in a clinical context. Gene therapy represents an innovating and appealing strategy for treatment of human diseases, which utilizes vehicles or vectors for delivering therapeutic genes into the patients' body. How...

application of therapeutic gene transfer in the treatment of genetic diseases is a notable progress but there are some disadvantages and limitations in it. the process of overcoming these barriers is a drastic change in gene delivery. recently, calcium phosphate nanoparticles alone, or in combination with viral and nonviral vectors, were found to have a positive effect on gene transfer especial...