The genetic and molecular mechanisms that control the development of capillary blood vessels during follicular development are beginning to be elucidated. Ovarian follicles contain and produce angiogenic factors that may act alone or in concert to regulate thecal angiogenesis. These factors are ultimately controlled by endocrine, paracrine and autocrine regulation in the ovary. Our recent study...

Angiogenesis is associated with follicular development and is regulated independently within each follicle potentially making the functioning of its vasculature critically important in determining its fate. This review examines the various ways in which follicular angiogenesis may be monitored, describes the follicular localisation and changes in pro- and anti-angiogenic factors that may regula...

Background: Adiponectin is an adipocytokines which is secreted from the adipose tissue of human and domestic animals. No information is available regarding the follicular fluid adiponectin concentrations in dairy cows. Therefore, the aim of the present study was to determine the follicular fluid adiponectin concentrations in different-sized follicles in the luteal phase of the estrous cycle in ...

Ovarian follicular development in the species follows a wave dynamics involving mostly 2wave or 3-wave cycles. Although there are still large gaps in our understanding of the etiopathogenic mechanisms underlying reproductive disorders in buffalo, available literature suggests alterations in ovarian dynamics at one or more stages of follicular development. This article gives a brief account of t...

Age-associated decline in oocyte quality is common in mammals. Oocytes take a long time to reach their full-grown size in large animals, and maternal physical conditions profoundly affect follicle development. Aging affects the oocyte itself as well as the surrounding environment, such as granulosa cells and follicular fluid. This review discusses age-associated changes that occur in granulosa ...

Most estrous cycles in cows consist of 2 or 3 waves of follicular activity. Waves of ovarian follicular development comprise the growth of dominant follicles some of which become ovulatory and the others are anovulatory. Ovarian follicular activity in cows during estrous cycle was studied with a special reference to follicular waves and the circulating concentrations of estradiol and progestero...

Background: Fatty acids are known to be critically important in multiple biological functions. Phospholipid fatty acids of follicular fluid, an important microenvironment for the development of oocytes, may contribute to the women’s fertility and the efficacy of assisted reproduction techniques. The aim of this study was to investigate the effect of fatty acid composition of follicular fluid ph...