BACKGROUND Increasing serum levels of uric acid (SUA) after menopause in women brought up a hypothesis that estrogenic effect may protectively regulate SUA. Estrogenic effect is a major etiology of uterine fibroids and fibrocystic breast disease. The study aimed to explore SUA among patients suffering from these diseases to enhance the hypothesis. METHODS Overall, 1349 female participants wer...

BACKGROUND Non-cancerous diseases of the breast have assumed increasing importance because of the public awareness of breast cancer. These benign diseases are a recognized important risk factor for later breast cancer which can develop in either breast. The risk estimate of these benign breast diseases has not been well established in sub Saharan Africa. Women with benign proliferative or atypi...

OBJECTIVE To investigate the magnitude of breast diseases, and its frequency distribution in different age groups in Hadramout, Yemen. METHODS This is a prospective study conducted at the Central Laboratory of Ibn-Sinna Hospital, Hadramout, Yemen from January 2006 to December 2009. Patients attending surgical units for breast problems were eligible. Patients were assessed clinically and refer...

AIM Fibrocystic mastosis (FCM) is defined by the totality of dystrophic changes of the mammary tissue, the grouping in the form of fibrosis of epithelial, cystic, metaplastic and hyperplastic alterations. A very good estimation of the cancer risk is related specifically to the microscopic aspect. Other factors, the family history as well as the presence of an inherited gene determining the incr...

BACKGROUND In Ghana data on breast disease is lacking. OBJECTIVE To describe the type of complaints presented at a specialist clinic. STUDY DESIGN A prospective descriptive study. SETTING The Komfo Anokye Teaching Hospital Breast Care Centre (KATH-BCC) METHOD: Data including the age, type of complaints, the clinical, radiological and histological diagnosis was obtained and recorded from a...

BACKGROUND Proliferative benign breast conditions are associated with elevated risk of breast cancer, whereas nonproliferative conditions are not strongly associated with risk. Factors acting before onset of hyperplasia might be associated with both benign conditions and breast cancer, whereas those on the proliferative disease-to-cancer pathway would be associated only with cancer. Soy isoflav...

Objective: To evaluate diagnostic performance of fine needle aspiration cytology[FNAC] in diagnosis of benign breast lesions. Methods: Women who had FNAC diagnosis of benign breast lesion were followed up with histopathological evaluation to assess the diagnostic accuracy of FNAC. Results: Out of sixty benign cases diagnosed on FNAC, fifty eight cases were benign and one case each of mastitis a...

Background:Various types of lesion from inflammation to carcinoma can affect the breast. Some lesions are common in young females while others are more common in elderly age group. Early presentation and prompt diagnosis is essential to relieve anxiety of nonneoplastic conditions, and in case of carcinoma, it can save the patient from metastases. Methods: A Retrospective study was conducted for...

We report a 33-year-old woman who presented with a breast lump which, on pathological examination, was found to be a hydatid cyst. There was no evidence of any coexistent lesion elsewhere. To our knowledge, this represents the first case of hydatid disease of the breast reported from Nepal.

Elastosis in the breast is an unusual phenomenon and its morphogenesis has not yet been fully ascertained. The degree of elastosis in the breast associated with benign diseases, including fibroadenoma and fibrocystic disease as well as with breast carcinoma, was examined with special reference to the correlation between the degree of epithelial proliferation and elastosis. Using the immunohisto...