conclusions special high-risk groups, including patients with ltbi, should be treated before receiving tnf-α inhibitors. the tuberculin skin test (tst) is a somewhat cost-effective test for the diagnosis of ltbi. however, its usefulness with respect to false results should be re-evaluated in this situation. results there were somewhat different approaches proposed by various researchers regardi...

objective(s): acquisition of tnf-α resistance plays role in the onset and growth of malignant tumors. previous studies have demonstrated that mcf-7 cell line and its doxorubicin resistant variant mcf-7/adr are resistant against the cytotoxic effects of tnf-α. in this study, we investigated the role of akt activation in resistance of mcf-7 and mcf-7/adr against tnf-α cytotoxicity. materials and ...

conclusions in the chinese han population that we studied, nafld patients who carry the tnf-α-238 ga polymorphism have an increased risk of developing cad. mechanisms underlying this potentially important association require further investigation. background cardiovascular events account for the main cause of death in patients with non-alcoholic fatty liver disease (nafld), and are largely infl...

Abstract Despite extensive research support, the role of diversification in current factor investing strategies remains neglected. This paper investigates whether well-designed multifactor portfolios should not only be based on firm characteristics, but also include portfolio effects. While alpha concentration approach mainly considers factor-specific diversified utilizes covariance estimators ...

background the 12-item general health (ghq-12) questionnaire is one of the most commonly used instruments in screening studies on mental health. objectives the current study aimed to examine the factor structure of the ghq-12 questionnaire among the students in iran. materials and methods it was a cross-sectional study in which 428 university students were recruited and completed the ghq-12. re...