The main goal of this research is to provide a more detailed investigation of the size-dependent response of magneto-electro-thermo-elastic (METE) nanobeams subjected to propagating wave, ...

Socially stressful environments induce a phenotypic dichotomy of coping measures for populations in response to a dominant aggressor and given a route of egress. This submission- (Stay) or escape-oriented (Escape) dichotomy represents individual decision-making under the stressful influence of hostile social environments. We utilized the Stress-Alternatives Model (SAM) to explore behavioral fac...

V3-glycan-targeting broadly neutralizing antibodies (bNAbs) are a focus of HIV-1 vaccine development. Understanding the viral dynamics that stimulate the development of these antibodies can provide insights for immunogen design. We used a deep-sequencing approach, together with neutralization phenotyping, to investigate the rate and complexity of escape from V3-glycan-directed bNAbs compared to...

Thermally activated escape in the presence of periodic external field is investigated theoretically and through analog experiments and digital simulations. The observed variation of the activation energy for escape with driving force parameters is accurately described by the logarithmic susceptibility (LS). The frequency dispersion of the LS is shown to differ markedly from the standard linear ...

abstract mutations have been described in all of the four open reading frames of the hepatitis b virus (hbv), however, from a clinical perspective the surface escape mutant is the most troublesome. hepatitis b surface antigen (hbsag) variants may impair diagnosis, or allow the virus to escape vaccine-induced immunity or passive immunoglobulin therapy. hbv mutants with amino acid substitutions, ...

conclusions these data will be beneficial for designing more advanced antibodies for the recognition of the hbsag in diagnostics. in addition, the results of this study may assist in the design or development of more effective hepatitis b vaccines. results the g145r mutation causes a considerable reduction in the immunogenic activity of the hbsag through a conformational change in the hbsag ant...

We study the escape of Brownian motion from the domain of attraction Ω of a stable focus with a strong drift. The boundary ∂Ω of Ω is an unstable limit cycle of the drift and the focus is very close to the limit cycle. We find a new phenomenon of oscillatory decay of the peaks of the survival probability of the Brownian motion in Ω. We compute explicitly the complex-valued second eigenvalue λ2(...

Experimental measurements of escape performance in fishes have typically been conducted in still water; however, many fishes inhabit environments with flow that could impact escape behavior. We examined the influences of flow and predator attack direction on the escape behavior of fish, using juveniles of the amphidromous Hawaiian goby Sicyopterus stimpsoni In nature, these fish must escape amb...