نتایج جستجو برای: epileptic drugs
تعداد نتایج: 235899 فیلتر نتایج به سال:
Association between ABCB1-T1236C Polymorphism and Drug-Resistant Epilepsy in Iranian Female Patients
Background: One third of epileptic patients are resistant to several anti-epileptic drugs (AED). P-glycoprotein (P-gp) is an efflux transporter encoded by ATP-binding cassette subfamily B member 1 (ABCB1) gene that excludes drugs from the cells and plays a significant role in AEDs resistance. Over-expression of P-gp could be a result of polymorphisms in ABCB1 gene. We studied the association of...
background and objective: epilepsy is a long-lasting central nervous system disorder that is accompany with spontaneous seizures and insufficiency in learning and memory. now drug treatment is the most common therapy but some patients do not research to suitable control of their seizures with current drugs. hence, new treatment is needed to help those patients that are unaffected to existing dr...
Objective: To identify the utilization pattern of antiepileptic drugs (AEDs) in a representative sample of the Pakistani population. To highlight the main risk factors associated with different forms of epilepsy. Methods: A retrospective drug utilization review study was conducted at three teaching institutions of Karachi. During the nine months study period, epileptic and non-epileptic patient...
OBJECTIVE This study was aimed at correlating the salivary and serum free concentrations of anti-epileptic drugs (carbamazepine, phenytoin and sodium valproate) in a population of neurological patients in a routine clinical setting. METHOD Twenty-seven paired serum/saliva specimens from 22 patients: 10 for carbamazepine, 8 for phenytoin and 9 for sodium valproate were obtained to study these ...
INTRODUCTION Increased blood homocysteine levels are a known cardiovascular risk factor. Epileptic patients on long-term treatment with antiepileptic drugs may present higher homocysteine levels and, consequently, a potential increase in cardiovascular risk. MATERIAL AND METHODS We conducted an observational case-control study to compare plasma levels of homocysteine, folic acid, and vitamin ...
how to cite this article: mahyar a, ayazi p, dalirani r, hosseini sm, daneshi kohan mm. serum thyroid hormone levels in epileptic children receiving anticonvulsivedrugs. iranian journal of child neurology 2011;5(4):21-24. objective the aim of this study was to investigate serum thyroid hormone levels in epileptic children receiving anticonvulsive drugs. materials & methods in this case- control...
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