نتایج جستجو برای: emperipolesis
تعداد نتایج: 125 فیلتر نتایج به سال:
Rosai Dorfman disease (RDD) or sinus histiocytosis with massive lymphadenopathy (SHML) is a rare disorder that typically manifests as lymphadenopathy and systemic symptoms.The authors report a 56 year old man who presented with massive generalised lymphadenopathy with haemolytic anaemia. Histopathological examination demonstrated lymphophagocytosis (emperipolesis) consistent with a diagnosis of...
Background Blau Syndrome (BS), a rare autoinflammatory disease characterized by non-caseating granulomas, is caused by gain-of-function mutations in NOD2. Crohn’s disease (CD) is associated with intestinal granulomas, and SNPs in NOD2. Emperipolesis, the ‘inside round about wandering’ of lymphocytes within other cells is a typical feature of Rosai-Dorfman disease, and seen occasionally in malig...
There are intense published data in literature related to cell engulfment phenomena such as emperipolesis, entosis and cell cannibalism. All these are closely related phenomena with a very fine line of differences. Its correct identification has a significant diagnostic and prognostic value. After extensive literature search, a gap of knowledge was found in concept designing and clarity about u...
S inus histiocytosis with massive lymphadenopathy (Rosai-Dorfman disease [RDD]) is a benign, idiopathic, self-limiting lymphoproliferative disease, described by Rosai and Dorfman in 1969. Extranodal manifestations represent about 43% of cases. The disease is classically accompanied by fever, malaise, leukocytosis, increased erythrocyte sedimentation rate, and hypergammaglobulinemia. Rosai-Dorfm...
Yau Ma Tei Dermatology Clinic, 12/F, Yau Ma Tei Specialist Clinic, 143 Battery Street, Kowloon, Hong Kong Rosai-Dorfman disease (RDD) is a benign idiopathic proliferative disorder. It commonly affects lymph nodes, but other organs can be involved. RDD limited to skin is rare. We report a 45-yearold Chinese man suffering from RDD. The first three skin biopsies revealed granulomatous inflammation...
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