A phenomenological mixture model is presented for interactions between biosynthesis of extracellular matrix (ECM) constituents and ECM linking in a scaffold seeded with chondrocytes. A system of three ordinary differential equations for average apparent densities of unlinked ECM, linked ECM and scaffold is developed along with associated initial conditions for scaffold material properties. Equa...

We propose a mathematical model of spiking neural network (SNN) that interacts with an active extracellular field formed by the brain matrix (ECM). The SNN exhibits irregular dynamics induced constant noise drive. Following neurobiological facts, neuronal firing leads to production ECM occupies space. In turn, components can modulate signaling and synaptic transmission, for example, through eff...

In this article, we estimate the vertical price transmission through the Iranian rice marketing chain by usingmonthly data from March 2000 to February, 2009 and error correction model (ECM).The causality testresults indicate that changes in the producer price clearly led changes in wholesale and retail prices. InProducer-Retail and Wholesale-Retail models, price transmission is asymmetric but i...

Background Much research went in the last two decades into the problem of tumor growth and drug delivery [1]. An extensive literature review [2] has shown that the most recent models for tumor growth are multicomponent models with or without diffuse interfaces among the constituents [3–10]. They all consider a malignant mass (tumor cells: TCs), host cells (HCs) and the interstitial fluid (IF) a...

We have previously demonstrated the increased metastatic potential of human prostate cancer circulating tumor cells (CTC), compared to their parental cells, in both orthotopic mouse models and the chick embryo model. In the current study, we asked whether an extracellular matrix (ECM), produced by human foreskin fibroblasts in culture, could inhibit PC-3 human prostate cancer CTC metastasis in ...

The Expectation Confirmation Model (ECM) is a popular model used to explain the continuance of information system usage. However, past studies have found that the ECM, based on extrinsic motivations (e.g. perceived usefulness, user satisfaction), has limitations insofar as people often have both intrinsic and extrinsic motivations simultaneously. This study used the belief of causal attribution...

The adhesion, mechanics, and motility of eukaryotic cells are highly sensitive to the ligand density and stiffness of the extracellular matrix (ECM). This relationship bears profound implications for stem cell engineering, tumor invasion and metastasis. Yet, our quantitative understanding of how ECM biophysical properties, mechanotransductive signals, and assembly of contractile and adhesive st...

Cerebral malaria (CM) is the most severe manifestation of human malaria yet is still poorly understood. Mouse models have been developed to address the subject. However, their relevance to mimic human pathogenesis is largely debated. Here we study an alternative cerebral malaria model with an experimental Plasmodium berghei Keyberg 173 (K173) infection in Sprague Dawley rats. As in Human, not a...

Extracellular matrix (ECM) critically impacts tumor progression and is influenced by both cancer and host tissue cells. While our understanding of cancer cell ECM remodeling is widespread, the importance of host tissue ECM, which provides initial congenial environment for primary tumor formation, is partly understood. Here, we report a novel role of epithelial cell-associated vacuolar ATPase 'a...

This paper aims to investigate the Fintech Service Acceptance on Student in Indonesia. The investigating of acceptance employs extended-ECM reveal student’s perception usefulness, confirmation, and satisfaction using fintech service. extend Expectation–confirmation model (ECM) technological self-efficacy (TSE) perceived ease use is used this research adoption study area. also adds trust factor ...