Energy-coupling factor (ECF) transporters form a new family of ATP-binding cassette (ABC) transporters and are widely used by prokaryotes to take up micronutrients from the environment. Instead of using the periplasmic solute-binding proteins (SBPs), ECF transporters use the membrane S proteins for substrate capture and translocation. In this review, we will focus on structural advances that ha...

The capacity of actively or passively sensitized guinea pig lung to react with antigen to release a factor specifically chemotactic for eosinophil leukocytes (ECF-A) has been demonstrated. The release of ECF-A was also accompanied by the elaboration of both histamine and SRS-A and the appearance of all these mediators exhibited a similar response in terms of the time course of passve sensitizat...

The present study was designed to assess the antiarthritic potential of ECF in collagen-induced arthritis (CIA) and explore its underlying mechanism. Methods. In vitro, lymphocyte proliferation assay was measured by CCK-8 kit. In vivo, the therapeutic potential of ECF on CIA was investigated; surface marker, Treg cell, and intracellular cytokines (IL-17A and IFN-γ) were detected by flow cytomet...

BACKGROUND Enterocutaneous fistulas (ECF) are debilitating and usually result following complex abdominal surgery. While there is an association with inflammatory bowel disease (IBD), a large number of fistulas occur after surgery not related to IBD. The consequences of ECF include short bowel syndrome and the need for long term parenteral nutrition.ECF can heal spontaneously and in the case of...

A peptide of approximately 300-400 daltons exhibiting in vitro chemotactic activity for human polymorphonuclear (PMN) leukocytes, with a preference for the eosinophil series, was isolated from extracts of anaplastic lung carcinomas of the large squamous cell type obtained from three patients with marked peripheral blood hypereosinophilia and eosinophilic infiltration of the tumors and surroundi...

BACKGROUND Nitric oxide (NO) is a compound with both protective and damaging effects on neurons. Quantification of NO metabolites in humans is limited by sample contamination with blood. In vivo cerebral microdialysis may offer an alternative approach as sampling of extracellular fluid (ECF) adjacent to neurons becomes possible. We investigate the prognostic value of brain ECF NO metabolites in...

An electro-conjugate fluid (ECF) is a kind of dielectric fluid that works as a functional/smart fluid generating a powerful jet flow (ECF jet) when subjected to a high d.c. voltage. The authors previously proposed the first liquid rate gyroscope in the world using ECF. The ECF liquid rate gyroscope proposed uses the drift of the ECF jet due to the Coriolis force when an angular motion is applie...

1. Renal sodium excretion is the primary determinant of sodium homeostasis. 2. Changes in sodium concentration in extracellular fluid (ECF) are associated with disorders of water balance. 3. Hypovolemia refers to losses of salt and water from the ECF, whereas dehydration is defined as primarily water loss from ECF. 4. Hypervolemia results when fluid accumulates in the ECF at a higher rate than ...

Gastric cancer was the 6th most frequent tumor worldwide in 2020. The prognosis of patients with gastric and gastrooesophageal junction (GEJ) adenocarcinoma is poor. Many efforts had been made to improve these patients’ prognosis, as adjuvant chemotherapy, chemoradiation perioperative chemotherapy. benefit overall survival (OS) disease free (DFS) chemotherapy first demonstrated MAGIC trial. FLO...

Globally, gastric cancer is the second most common cause of cancer-related death. The majority of gastric cancer patients will have at presentation or will ultimately develop overt metastatic disease. Meta-analysis has demonstrated not only that systemic chemotherapy can improve survival in patients with advanced disease but also that the best survival results in earlier randomized studies have...