Introduction. Currently, there is a renaissance of phenazopyridine in world urology. The aim this work was to study the analgesic and antidysuric effects phenazopyridine, as well evaluate efficacy tolerability combination with fosfomycin for treatment acute uncomplicated cystitis women working age. Materials methods. In 2020–2022 multicenter randomized open conducted. This involved 224 aged 18 ...

Background: Labour dystocia is the commonest indication for emergency caesarean section in nulliparas, and occurs when progress of labour abnormally slow. may be caused by abnormalities uterine contractions, slow cervical dilatation, or mechanical disproportion between foetal presenting part maternal pelvis. Augmentation with oxytocin traditional management as it enhances contractions. At times...

BACKGROUND This study aimed to assess the efficacy and safety of drotaverine hydrochloride (DHC) in Chinese patients with irritable bowel syndrome (IBS). METHODS Totally, 144 patients with IBS were included and randomly divided into treatment group and placebo group in a 1:1 ratio. Patients received either DHC or placebo 80-mg tablet, 3 times daily for a total of 4 weeks. The primary outcome ...

To develop a simple and sensitive method for the simultaneous estimation of drotaverine HCL (DRH) and aceclofenac (AF) using RP-HPLC. The HPLC separation was achieved on a thermo column (250 mm × 4.6 mm, 5μ) with an isocratic mixture of acetonitrile and 5 mM of ammonium acetate in the ratio of 65:35, pH adjusted to 4.5 at a flow rate of 1.0 ml/min and the detection at 285nm. The method was vali...