Thrombocytopenia is a known potential side effect of hemodialysis, however, it is rarely seen in patients who undergo hemodialysis using biocompatible membranes. This case demonstrates hemodialysis-associated thrombocytopenia with use of biocompatible dialysis membranes that expose blood directly to polysulfone. The thrombocytopenia resolved in this patient when the dialysis membrane was change...

We have ever developed micro dialysis system that consists of micro channels and polyethersulfone (PES) membranes. However, when blood was used in dialysis experiments, platelets adhered to the surface of membrane and performance of the membrane degraded. Therefore, we modify the surface of PES membranes by coating fluorinated diamond-like carbon (F-DLC). We examined antithrombogencity of the F...

Patients undergoing maintenance hemodialysis therapy have increased mortality due to cardiovascular disease. One possible etiologic factor for this increased mortality is the lipid abnormalities associated with chronic renal failure. These include elevated triglyceride (TG) and decreased high-density lipoprotein (HDL) concentrations. Lipoprotein profiles of patients undergoing chronic hemodialy...

GUIDELINE RECOMMENDATIONS • We recommend that either synthetic or cellulosic membranes be used for symptomatic intra-dialytic hypotension as synthetic membranes offer no benefit over cellulosic membranes (1C). • We recommend that high-flux membranes be used to remove molecules such as beta-2 microglobulin because they have been shown to achieve lower serum levels (1A). • We suggest there are po...

The handling of low, middle and high molecular weight markers was examined in seven stable dialysis patients during hemofiltration with different membranes. Four membranes were examined in a randomized, crossover order (polysulfone, polyamide, AN69 polyacrylonitrile, Asahi polyacrylonitrile) by measuring plasma and dialysate concentrations of phosphate, creatinine, vitamin B12, beta 2-microglob...

Hemodialysis is frequently complicated by hypotension and associated symptoms. It has been suggested that these symptoms may be related to the biochemical changes caused by cellulosic dialysis membranes. In this study, a prospective randomized crossover trial was conducted comparing the incidence of hypotension and acute symptoms during dialysis with large-surface-area (1.6 m2) cellulosic (cupr...

Lipid abnormalities are common in patients with renal disease, probably contributing to the high incidence of cardiovascular diseases in this population. In this study we determined the plasma and erythrocyte lipid profile in patients with chronic renal failure (CRF) along 30 months under hemodialysis. In the same patients the influence of cuprophane and polysulfone dialysis membranes on the fa...

Composite membranes for dialysis were prepared by a Loeb-Sourirajan (L-S) phase inversion process. After adding nanocrystalline cellulose (NCC), the ultrafiltration coefficient of the dialysis membrane could reach 48.37 L•m•h•mmHg. The clearance of lysozyme and urea could reach 70.25 % and 90.38 %, respectively. Simultaneously, the retention ratio of BSA could remain over 96%. Afterwards, in or...