Intensive blood glucose control can prevent the initiation and progression of diabetic complications. However, the impacts of intensive therapy against diabetic complications might be limited, because of difficulty in maintaining blood glucose concentrations close to the normal range or other unknown reasons. Thus, another approach based on the elucidation of mechanisms of diabetic complication...

People with diabetes mellitus have a high risk of anxiety and stress and anxiety is higher in patients with diabetes who have long-term complication. The aim of this study was to assess and compare the prevalence of anxiety and stress in diabetic patients with and without complication attending to diabetes clinic of Ebn Sina hospital of Delfan, Iran. In this descriptive-comparative study, 239 t...

Diabetes has become a major global health problem. The elucidation of characteristic metabolic alterations during the diabetic progression is critical for better understanding its pathogenesis, and identifying potential biomarkers and drug targets. Metabolomics is a promising tool to reveal the metabolic changes and the underlying mechanism involved in the pathogenesis of diabetic complications...