Intramuscular formulations of antipsychotics can be sub-divided into two groups on the basis of their pharmacokinetic features: short-acting preparations and long-acting or depot preparations. Short-acting intramuscular formulations are used to manage acute psychotic episodes. On the other hand, long-acting compounds, also called "depot", are administered as antipsychotic maintenance treatment ...

There are subtle, and yet critical and unique differences that distinguish the depot maintenance, repair, and overhaul (MRO) domain from production manufacturing. These differences motivate the need for more efficient ways to capture the essence of the depot MRO domain dynamics. The authors provide an informal characterization of the depot MRO by highlighting some of the major differences. Alon...

OBJECTIVE To find the time of the serum gonadotropin peak after depot leuprolide injection in children and to show that depot leuprolide therapy can be monitored by measuring serum luteinizing hormone (LH) immediately after injections. STUDY DESIGN We measured concentrations of leuprolide, LH, and follicle-stimulating hormone (FSH) at multiple time points before and after the first dose of de...

Cache depot is a performance enhancement technique on cache-coherent non-uniform memory access (CCNUMA) multiprocessors, in which nodes in the system store extra memory blocks on behalf of other nodes. In this way, memory requests from a node can be satisfied by nearby depot nodes without going all the way to the home node. This not only reduces memory access latency and network traffic, but al...

AIMS AND METHOD To establish if participants with schizophrenia receiving depot antipsychotics had less insight than similar participants receiving oral atypical antipsychotics.We assessed the difference between these two groups. RESULTS Participants on oral antipsychotics had greater insight than those on depot antipsychotics (ITAQ, P=0.01). In the multiple regression analysis, only receiving ...

AIMS AND METHOD To establish if participants with schizophrenia receiving depot antipsychotics had less insight than similar participants receiving oral atypical antipsychotics.We assessed the difference between these two groups. RESULTS Participants on oral antipsychotics had greater insight than those on depot antipsychotics (ITAQ, P=0.01). In the multiple regression analysis, only receiving ...

Depot-holders are women from the community who promote good health practice and use of clinics. They keep a stock of contraceptives and oral rehydration salts to supply other women and are paid some incentives. In 2003, the NGO Service Delivery Program (NSDP) introduced depot-holders in three types of urban area in Bangladesh as a pilot. This evaluation study was carried out to: (a) establish a...

We consider the vehicle routing problem with stochastic demands (VRPSD) on tree structured networks with a single depot. The problem we are concerned with in this paper is to find a set of tours for the vehicle with minimum expected length. Every tour begins at the depot, visits a subset of customers and returns to the depot without violating the capacity constraint. Randomized approximation al...

BACKGROUND Depot antipsychotic medication is used widely in the treatment and prophylaxis of severe mental illness. AIMS To review the literature on patient and nurse satisfaction with, and attitudes towards, depots. METHOD A systematic search of Medline, Embase, PsycINFO, CINAHL and The Cochrane Library was undertaken, along with citation searches. Studies were selected if satisfaction/att...