During the production of fine metal powder using vacuum induction melting gas atomization (VIGA) technology, problem nozzle clogging is often encountered. The viscosity melt one key factors causing nozzle. To visualize mechanism nozzle, volume fluid (VOF) model combined with large eddy turbulence was used to simulate nozzle-clogging process an alloy in primary zone. results show that, increase ...

Administration of drugs through enteral feeding tubes can be a simple way by which infants and children can receive medications, but it introduces concerns about potential blockage of the tube. The risk of feeding tubes becoming blocked is greater with small-diameter feeding tubes and low flush volumes.Tube blockage is disruptive to patient care, and replacing tubes can be uncomfortable for the...

Nasogastric tubes are often inserted in intensive care settings, the emergency department and hospital wards. Common indications for nasogastric tubes are gastric decompression to palliate bowel obstruction, preventing aspiration in intubated patients and for the delivery of enteral nutrition or medication. A case of pneumothorax following nasogastric tube insertion in a 63-year-old neurosurgic...

In this paper, computational fluid dynamics (CFD) is utilized to characterize a prototype biolistic delivery system, the biomedical device based on the contoured-shock-tube design (CST), with the aim at investigating shocks induced flow instabilities within the contoured shock tube. The shock/interface interactions, the growth of perturbation at an interface between two fluids of different dens...

context maternal serum human chorionic gonadotropin (hcg) and alpha fetal protein (afp) were originally introduced to detect trisomy 21 and neural tube defects. however, in the absence of aneuploidy or neural tube defects, mid-trimester maternal serum hcg and/or maternal serum afp associated with adverse pregnancy outcomes. pregnancies with unexplained mid-trimester elevation in maternal serum ...

A novel drug delivery vehicle that specifically targets using ultrasound radiation force (USRF) and biotin-avidin interactions is presented. Model vehicles consist of avidinated fluorescent nanobeads bound directly to the biotinylated lipid shells of preformed microbubbles. USRF was used to deflect the vehicle from the center of flow to a tube surface in order to facilitate receptor-ligand medi...

BACKGROUND A fatal incident was reported when a mechanical ventilated patient received nebulization of a reconstituted Relenza® formulation. We propose a delivery system to introduce Relenza and other inhalation dry powders to intubated patients to avoid accidental fatalities in the future. METHODS This is a bench study demonstrating the feasibility of a delivery system to introduce dry powde...

The objective of this project is to introduce students to the concepts of diffusion, polymers and polymerization reactions, and enzyme mediated reactions by designing and testing a controlled release drug delivery system. These types of systems are also referred to as localized drug delivery because an implant that releases drugs is placed directly into diseased tissue. Here, we use Jell-O c ©a...

abstract sirenomelia is a rare anomaly of caudal region of the body presented with fusion of lower limbs in which genito-urinary, gastrointestinal, cardiovascular and neural tube anomalies are found in most cases. we introduce a case of severe oligohydramnios, which had characteristic aspects of sirenomelia at the time of delivery and review the pertinent articles. all in all it is our aim to p...

In patients with severe acute pancreatitis (AP), enteral nutrition is delivered by nasojejunal (NJ) tube to minimise pancreatic stimulation. Nasogastric (NG) feeding represents an alternative route. The primary objective of this systematic review and meta-analysis was to evaluate the efficacy of NG feeding. Secondary objectives were to compare the NG and NJ routes and assess the side effects of...