PURPOSE Removal of CO₂ is much efficient during high-frequency oscillatory ventilation (HFOV) for preterm infants. However, an optimal carbon dioxide diffusion coefficient (DCO₂) and tidal volume (VT) have not yet been established due to much individual variance. This study aimed to analyze DCO₂ values, VT, and minute volume in very-low-birth-weight (VLBW) infants using HFOV and correlates with...

STUDY OBJECTIVE To determine pretreatment factors that predict for pulmonary toxic reactions after high-dose chemotherapy containing carmustine (BCNU) and to determine the utility of prednisone in preventing pulmonary toxic reactions. DESIGN Retrospective review. SETTING Tertiary care referral center. PATIENTS Forty-five patients with relapsed or refractory lymphoma and 27 patients with b...

This paper introduces a new programming model for distributed systems, distributed composite objects (DCO), to meet efficient implementation, transparency, and performance demands of distributed applications with cooperating users connected through the internet. It allows the representation of an object as a collection of sub-objects and enhances the object distribution concept by implementing ...

The purpose of this study was to compare the effectiveness of damage-control orthopedics (DCO) vs early total care (ETC) in the treatment of borderline high-energy pelvic fractures. Seventy-two patients with borderline high-energy pelvic fractures were retrospectively reviewed; 39 received DCO and 33 received ETC. Demographic data and initial injury severities were comparable between groups, ex...

This paper introduces a new programming model for distributed systems, distributed composite objects (DCO), to meet efficient implementation, transparency, and performance demands of distributed applications with cooperating users connected through the internet. DCO model incorporates two basic concepts. The first is composition, by which an object is partitioned into sub-objects that together ...

Geoscience researchers are increasingly dependent on informatics and the Web to conduct their research. Geoscience is one of the first domains that take lead in initiatives such as open data, open code, open access, and open collections, which comprise key topics of Open Science in academia. The meaning of being open can be understood at two levels. The lower level is to make data, code, sample...

We evaluated the signaling pathways involved in regulating vascular endothelial growth factor (VEGF), a potent angiogenic growth factor, in response to natural and synthetic progestins in breast cancer cells. Inhibition of the phosphoinositide-3'-kinase (PI3-kinase) signaling pathway or the specificity protein-1 (SP-1) transcription factor abolished both progesterone- and medroxyprogesterone ac...

Pentoxifylline is a xanthine derivative with hemorrheologic and vascular properties that may improve gas exchange in patients with chronic obstructive pulmonary disease (COPD). We tested this hypothesis in 12 patients with COPD (mean FEV1 = 40 percent predicted; mean DCO, 8.6 ml/min/mm Hg) randomly divided into a treatment and control group and six healthy volunteers. Following establishment of...

A Digitally Controlled Oscillator (DCO) for the frequency band of 1700-1900 MHz is presented. This architecture achieves a frequency resolution less than 1-kHz. The DCO is a part of an All-Digital Phase-Locked Loop (ADPLL) for GSM-1800 and GSM-900 applications implemented in a 0.18 μm CMOS process. In this architecture an 18-bit delta sigma digital to analog converter and a voltage controlled L...

We report on the detection of DCO+ and, tentatively, DCN in their rotational J=2–1 transitions towards the N159 region in the Large Magellanic Cloud (LMC). These detections of deuterated molecules in an extragalactic source complement those already published by Chin et al. (1996). The resulting estimate of theHCO+/DCO+ abundance ratio is 120+60 −60 (total 2σ uncertainties).Assuming aGalacticD/H...