نتایج جستجو برای: contractile response

تعداد نتایج: 993894  

H SADRAEI, V HAJHASHEMI,

Ketotifen is a benzocycloheptathiophene with a range of pharmacological activities. The present study was carried out to evaluate the action of ketotifen on isolated rat bladder contractions induced by KCI and acetylcholine, compared with the effects of other drugs. Ketotifen (5 µM) reduced the response to acetylcholine on rat isolated bladder without altering the maximum response and shift...

Journal: :medical journal of islamic republic of iran 0
h sadraei from the department of pharmacology, school of pharmacy and pharmaceutical sciences, isfahan university of medical sciences ,isfahan, i.r. iran. v hajhashemi

ketotifen is a benzocycloheptathiophene with a range of pharmacological activities. the present study was carried out to evaluate the action of ketotifen on isolated rat bladder contractions induced by kci and acetylcholine, compared with the effects of other drugs. ketotifen (5 µm) reduced the response to acetylcholine on rat isolated bladder without altering the maximum response and shifted t...

Journal: :Nihon Heikatsukin Gakkai zasshi 1984
M Yoshida T Koeda

The present study was undertaken to investigate the effects of aminobenzyl penicillin (AB-PC), methylchlorophenyl isoxazolyl penicillin (MCI-PC), and 6-aminopenicillanic acid (6-APA) on the contractile response of guinea-pig urinary bladder. AB-PC, MCI-PC, and 6-APA, respectively, diminished the intramural electrical stimulation-induced contractile response. AB-PC had almost no effect on the co...

Journal: :iranian biomedical journal 0
محمدرضا واعظ مهدوی mohammad reza vaez mahdavi مهرداد روغنی mehrdad roghani توراندخت بلوچ نژاد tourandokht baluchnejadmojarad فرشاد روغنی دهکردی farshad roghani dehkordi

the present study was undertaken to determine whether two-month treatment of streptozotocin (stz)-diabetic rats with aqueous leaf extract of trigonella foenum-graecum (tfg 200 mg/kg i.p.) could improve thoracic aortic responsiveness and to evaluate its endothelium dependency. for this purpose, vascular responses to kcl and noradrenaline (na) were measured. diabetic state significantly increased...

2005
YOKU NAKAGAWA

3. Lcvine S, Pagan J: Effects of ischemia and other procedures on the brain and retina of thegerbil. ExpNeurol 16: 255-262, 1966 4. Kahn K. The natural course of experimental cerebral infarction in the gerbil. Neurology (Minneap) 22: 510-515, 1972 5. Rosenblum WI: Reactivity of cerebral blood vessels after carotid ligation in the gerbil. Stroke 9 (abst) 102, 1978 6. Welch KMA, Chabi E, Buckingh...

همایونفر, همایون, ایزدپناه, اسماعیل, محمودیان, مسعود, شفیعی, معصومه,

Diabetes mellitus is one of the most common endocrine disorders with increasing prevalence. Cardiovascular complications are among the major causes of death in diabetic patients. Type II diabetes mellitus is generally treated with sulfonylureas. There are controversial reports regarding adverse cardiovascular effects of these drugs. Also evidence exists about differences in side effec...

Ali Khoshbaten , Ali Norouzzadeh , Alireza Asgari , Mustafa Mohammadi , Reza Badalzadeh ,

Background: There are controversial reports about the exact mechanisms of lead-induced hypertension, but many factors such as alteration in the responsiveness of cardiovascular system to endogenous substances including catecholamines could be one of the mechanisms involved. In present study, the effect of exposure to 100 ppm lead acetate by drinking water (in the periods of 4, 8 and 12 weeks)...

Journal: :Circulation research 1984
C L Seidel R M Lewis R Bowers R D Bukoski H S Kim J C Allen C Hartley

Saphenous veins are used extensively to replace stenotic coronary arteries. However, the contractile and biochemical adaptations of grafted veins are unknown. The three purposes of this work were to characterize the contractile properties of grafted veins, to determine whether altered contractile characteristics were associated with quantitative changes in actin, myosin and collagen, and to det...

2005
PATRICIA M. ARISTEGUI MARIA AMELIA ENERO

Prostaglandin F^ (PGFjJ In a concentration that did not induce vascular contraction (10~ M) potentiated the dose-response curves to norepinephrine and 5-hydroxytryptamine and the contractile response induced by potassium (60 or 100 mM) in isolated mesenteric vascular bed of the rat. After prostaglandin inhibitor treatment with indomethacin (10~ M), the dose-response curve to norepinephrine was ...

F Falahi K Nasri M Roghani

Background & Aims: Considering increasing incidence of cardiovascular disorders in diabetes mellitus and some evidence on antioxidant and antidiabetic potentials of naringenin, this study was conducted to evaluate the beneficial effects of 6-week administration of naringenin on contractile reactivity of isolated thoracic aorta in diabetic rats. Methods: Male Wistar rats were divided into contro...

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