It has been unclear whether chromosomally integrated human herpesvirus 6 (ciHHV-6) can be activated with pathogenic effects on the human body. We present molecular and virological evidence of ciHHV-6A activation in a patient with X-linked severe combined immunodeficiency. These findings have significant implications for the management of patients with ciHHV-6.

pyoderma vegetans (pv) is a rare inflammatory disorder characterized by vegetating pustules and plaques affecting the skin and mucosal membranes. it is believed that this entity is mostly associated with inflammatory bowel disease (ibd), chronic malnutrition, human immunodeficiency virus (hiv), malignancies, and other immunocompromised states. pyoderma vegetans occurs more commonly in young and...