BACKGROUND Physicians' financial relationships with the pharmaceutical industry are controversial because such relationships may pose a conflict of interest. It is unknown to what extent industry support of medical education and research influences the opinions and behavior of clinicians and researchers. The recent debate over the safety of calcium-channel antagonists provided an opportunity to...

Calcium antagonists comprise 2 main subclasses, dihydropyridines and nondihydropyridines, and have been studied extensively in hypertensive patients. Early meta-analyses suggested that short-acting calcium antagonists were associated with higher mortality rates resulting from cardiovascular events and other etiologies. Recent meta-analyses failed to show any substantive difference between long ...

Yi-Chung Hsieh, Ying-Ru Chen, Err-Lieh Hsu and Rong Kou (2003) Pharmacological effects of calcium channel agtagoinsts on juvenile hormone acid release and intracellular calcium level in the corpora allata of adult male Mythimna loreyi (Lepidoptera: Noctuidae). Zoological Studies 42(2): 336-345. The pharmacological effects of calcium channel antagonists on the in vitro release of juvenile hormon...

BACKGROUND Secondary ischaemia is a frequent cause of poor outcome in patients with subarachnoid haemorrhage (SAH). Its pathogenesis has been incompletely elucidated, but vasospasm probably is a contributing factor. Experimental studies have suggested that calcium antagonists can prevent or reverse vasospasm and have neuroprotective properties. OBJECTIVES To determine whether calcium antagoni...