The endogenous production of unsaturated fatty acids (FA), particularly some monounsaturated FA (%MONO) and nearly all conjugated linoleic acids, is regulated by the 9-desaturase activity. The aims of this study were to assess the variation of this enzymatic activity within lactation, across dairy breeds, and to estimate its genetic parameters. The ratios of C14:1 cis-9 to C14:0, C16:1 cis-9 to...

A major part of the palmitic acid (C16:0) generated by fatty acid synthase is converted into stearic acid (C18:0) via carbon chain elongation. Here, we describe the cloning and expression of a rat hepatic enzyme, rELO2, responsible for the elongation of C16:0, presumably at the condensing reaction. Heterologous expression experiments in a yeast, Saccharomyces cerevisiae, demonstrated the elonga...

Intercalation of very long molecules into the structure multi-layered graphene oxide (GO) was studied using example 1-hexadecanol (C16), an alcohol molecule with 16 carbon atoms. Brodie graphite (BGO) immersed in excess liquid C16 just above melting point shows expansion c-unit cell parameter from ∼6 Å to ∼48.76 forming a two densely packed layers perpendicular orientation relative GO planes (α...

Effective inhibitors of invasion and metastasis represent a serious unmet clinical need. We have recently identified 4-fluoro-3',4',5'-trimethoxychalcone or C16 as a potent anti-invasive molecule. In this paper, we report on the development of an optimized vehicle for oral administration of C16. We also explore its pharmacokinetic and toxicity profile in rodents as a prelude to a broad-scope ev...

Aim: Determine the effect of dietary fats with different fatty acid composition on biosynthesis oleic and its metabolic precursors in liver .
 Methods: High linoleic sunflower oil (HLSO), high (HOSO) palm (PO) were used. Rats fed a semi-synthetic fat-free diet (FFD) fat diets containing 5 % above oils (instead starch) for 30 days. Liver lipids divided into 3 fractions: neutral (NL), phosph...

Our objective was to perform a series of meta-analyses evaluate the effects diets supplemented with saturated free fatty acid (FA) supplements (SFAA) compared nonfat control (CON) on nutrient digestibility and production responses lactating dairy cows determine whether experimental design affects SFFA. We divided SFFA into C16:0-enriched (PALM, FA ≥80% C16:0) C16:0+C18:0-enriched (MIX, C16:0+C1...

In this study, oil was extracted from the liver and visceral fat of Patin (Pangasianodon hypophthalmus) and refined. The yield of oil after refining was 49.98%. The major yield loss (34.20%) happened during the degumming procedure. Fatty acids found in the crude and refined oil were C12:0, C14:0, C14:1, C16:0, C16:1, C18:0, C18:1, C18:2, C18:3, C18:4, C20:0, C20:1, C20:4, C20:5, and C22:6. The ...

in this study,oil was extracted from the liver and visceral fat of patin (pangasianodon hypophthalmus) and refined. the yield of oil after refining was 49.98%. the major yield loss (34.20%) happened during the degumming procedure. fatty acids found in the crude and refined oil were c12:0, c14:0, c14:1, c16:0, c16:1, c18:0, c18:1, c18:2, c18:3, c18:4, c20:0, c20:1, c20:4, c20:5, and c22:6. the d...

Previous studies have shown that prevention of leukocyte infiltration by targeting integrins involved in transendothelial migration may suppress the clinical and pathological features of neuroinflammatory disease. This study was designed to investigate the effects of C16, an ανβ3 integrin-binding peptide, in an acute experimental allergic encephalomyelitis (EAE) rat model. Multiple histological...